Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | CASR | P41180 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Water SCHEMBL11091187 | 0.98 | PKM (0.57) | PKMALDH1A1HSD17B10CYP1A2CASP6 | |
| SCHEMBL3022743 | 0.98 | PKM (0.57) | PKMALDH1A1HSD17B10CYP1A2CASP6 | |
| Nitrogen SCHEMBL6249279 | 0.97 | PKM (0.56) | PKMALDH1A1HSD17B10CYP1A2CASP6 | |
| SCHEMBL10788098 | 0.87 | LMNA (0.68) | PKMALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL15461385 | 0.86 | ALDH1A1 (0.58) | PKMALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL30266262 | 0.86 | ALDH1A1 (0.58) | PKMALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL11334838 | 0.85 | CA12 (0.65) | ALDH1A1CASRPOLBRAB9ALMNA | |
| SCHEMBL7495022 | 0.84 | PKM (0.57) | PKMALDH1A1HSD17B10CYP1A2POLB | |
| SCHEMBL7495027 | 0.84 | CA1 (0.69) | POLB | |
| SCHEMBL1036779 | 0.84 | PKM (0.57) | PKMALDH1A1HSD17B10CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103123671-B | The target gene Rv2780 for the treatment of tuberculosis inhibitor screening and application | HUAZHONG AGRICULTURAL UNIVERSITY (CN) | 2015-11-11 | — | — | CN | claimed |
| CN-103123671-A | Target gene Rv0233 screened by antituberculous inhibitor and application | UNIV HUAZHONG AGRICULTURAL | 2013-05-29 | — | — | CN | claimed |
| EP-0095177-B1 | PROCESS FOR THE PREPARATION OF N-ACETYLAMINO-ARYL-SULPHONIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-24 | — | — | EP | claimed |
| JP-4356456-A | — | — | None | — | — | JP | disclosed |
| JP-4356455-A | — | — | None | — | — | JP | disclosed |
| WO-2023212019-A1 | PYRIMIDINONE-CONTAINING 17-BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 13 INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2023-11-02 | — | — | WO | disclosed |
| CN-116413231-A | Method for detecting trace diazonium salt in azo compound slurry | 沈阳化工研究院有限公司 | 2023-07-11 | — | — | CN | disclosed |
| US-8419848-B2 | Disazo compounds and their use in ink-jet printing | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2013-04-16 | — | — | US | disclosed |
| US-8038781-B2 | Ink composition, inkjet recording ink and inkjet recording method | FUJIFILM CORPORATION (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20110200800-A1 | Disazo Compounds and Their Use in Ink-Jet Printing | FUJIFILM CORPORATION (JP) | 2011-08-18 | — | — | US | disclosed |
| US-20100210603-A1 | NOVEL SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE | TUNG ROGER D | 2010-08-19 | — | — | US | disclosed |
| US-5585397-A | VIRICIDES | VERTEX PHARMACEUTICALS, INCORPORATED (US) | 1996-12-17 | — | — | US | disclosed |
| EP-0659181-A1 | SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1995-06-28 | — | — | EP | disclosed |
| WO-1994005639-A1 | SULFONAMIDE INHIBITORS OF HIV-ASPARTYL PROTEASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 1994-03-17 | — | — | WO | disclosed |
| EP-0555699-A2 | Aromatic compounds substituted by an urethane group and by an amino group | BAYER AG (DE) | 1993-08-18 | — | — | EP | disclosed |
| JP-H04356456-A | PRODUCTION OF N-ACETYLAMINOARYLSULFONIC ACID CHLORIDE | HOECHST AG | 1992-12-10 | — | — | JP | disclosed |
| JP-H04356455-A | SOLID, ISOLATED ANHYDROUS N-ACETYLMETANILIC ACID | HOECHST AG | 1992-12-10 | — | — | JP | disclosed |
| EP-0095177-B1 | PROCESS FOR THE PREPARATION OF N-ACETYLAMINO-ARYL-SULPHONIC ACIDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-07-24 | — | — | EP | disclosed |
| US-4487725-A | Process for the preparation of N-acetylaminoarylsulfonic acids in sulfuric acid as solvent | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-11 | — | — | US | disclosed |
| EP-0095177-A1 | Process for the preparation of N-acetylamino-aryl-sulphonic acids | HOECHST AKTIENGESELLSCHAFT (DE) | 1983-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100210603-A1 | NOVEL SULFONAMIDE INHIBITORS OF ASPARTYL PROTEASE | SPINT2, PRSS1, DNPEP | PKM 2645/4885ALDH1A1 1532/4885HSD17B10 1297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.