Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.35 |
| ▸ | SCD | O00767 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.33 |
| ▸ | NQO1 | P15559 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13662226 | 0.97 | KCNH2 (0.43) | KCNH2NT5ECYP3A4JAK2MIF | |
| SCHEMBL13662234 | 0.91 | KCNH2 (0.43) | KCNH2NT5ECYP3A4MIFSCD | |
| SCHEMBL13662230 | 0.89 | KCNH2 (0.41) | KCNH2NT5ECYP3A4JAK2MIF | |
| SCHEMBL13663814 | 0.89 | NT5E (0.41) | KCNH2NT5ECYP3A4JAK2MIF | |
| SCHEMBL13662231 | 0.87 | KCNH2 (0.40) | KCNH2JAK2MIF | |
| SCHEMBL18116833 | 0.87 | KCNH2 (0.39) | KCNH2NT5ECYP3A4JAK2MIF | |
| SCHEMBL18638720 | 0.86 | KCNH2 (0.38) | KCNH2NT5EJAK2MIFPI4KB | |
| SCHEMBL18638158 | 0.85 | KCNH2 (0.41) | KCNH2NT5ECYP3A4JAK2MIF | |
| SCHEMBL18638619 | 0.85 | KCNH2 (0.37) | KCNH2NT5EJAK2PI4KBEGLN1 | |
| SCHEMBL18266816 | 0.85 | KCNH2 (0.44) | KCNH2CYP3A4JAK2MIFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141905-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | Promega Corporation (US) | 2017-03-15 | — | — | EP | disclosed |
| EP-2269064-B1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | PROMEGA CORP (US) | 2016-11-30 | — | — | EP | disclosed |
| US-9459249-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |