Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | NT5E | P21589 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | NAMPT | P43490 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15186591 | 0.94 | KCNH2 (0.37) | KCNH2NT5EJAK2PI4KBEGLN1 | |
| SCHEMBL18116833 | 0.91 | KCNH2 (0.39) | KCNH2NT5EJAK2PI4KBEGLN1 | |
| SCHEMBL18638720 | 0.90 | KCNH2 (0.38) | KCNH2NT5EJAK2PI4KBEGLN1 | |
| SCHEMBL18116829 | 0.85 | KCNH2 (0.44) | KCNH2NT5EJAK2PI4KBEGLN1 | |
| SCHEMBL13662230 | 0.84 | KCNH2 (0.41) | KCNH2NT5EJAK2PI4KBEGLN1 | |
| SCHEMBL13662226 | 0.82 | KCNH2 (0.43) | KCNH2NT5EJAK2PI4KB | |
| SCHEMBL13662231 | 0.79 | KCNH2 (0.40) | KCNH2JAK2 | |
| SCHEMBL25457426 | 0.78 | KCNH2 (0.46) | KCNH2NT5ENAMPT | |
| SCHEMBL18266816 | 0.76 | KCNH2 (0.44) | KCNH2JAK2 | |
| SCHEMBL21549540 | 0.76 | TP53 (0.46) | KCNH2NT5ENAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3141905-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | Promega Corporation (US) | 2017-03-15 | — | — | EP | disclosed |