Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.39 |
| ▸ | NT5E | P21589 | 2/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 4/20 | 0.34 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.31 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MMP14 | P50281 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18116829 | 0.89 | KCNH2 (0.44) | KCNH2JAK2NT5EEGLN1MIF | |
| SCHEMBL18804779 | 0.89 | KCNH2 (0.35) | KCNH2JAK2EGLN1 | |
| SCHEMBL18116833 | 0.87 | KCNH2 (0.39) | KCNH2JAK2NT5EEGLN1MIF | |
| SCHEMBL13662226 | 0.86 | KCNH2 (0.43) | KCNH2JAK2NT5EMIFPI4KB | |
| SCHEMBL18638720 | 0.85 | KCNH2 (0.38) | KCNH2JAK2NT5EEGLN1MIF | |
| SCHEMBL13637125 | 0.85 | MCHR1 (0.34) | KCNH2HDAC6KMT2A | |
| SCHEMBL18638619 | 0.84 | KCNH2 (0.37) | KCNH2JAK2NT5EEGLN1PI4KB | |
| SCHEMBL15186591 | 0.84 | KCNH2 (0.37) | KCNH2JAK2NT5EEGLN1PI4KB | |
| SCHEMBL18266816 | 0.83 | KCNH2 (0.44) | KCNH2JAK2MIFHDAC6ALB | |
| SCHEMBL13662231 | 0.83 | KCNH2 (0.40) | KCNH2JAK2MIFHDAC6ALB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9932365-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170283456-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-10-05 | — | — | US | disclosed |
| US-9689868-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2017-06-27 | — | — | US | disclosed |
| EP-2626703-B1 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORP (US) | 2017-05-03 | — | — | EP | disclosed |
| EP-3141905-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | Promega Corporation (US) | 2017-03-15 | — | — | EP | disclosed |
| US-20170016888-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT | 2017-01-19 | — | — | US | disclosed |
| EP-2269064-B1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | PROMEGA CORP (US) | 2016-11-30 | — | — | EP | disclosed |
| US-9459249-B2 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2016-10-04 | — | — | US | disclosed |
| EP-2626703-A1 | Protein labeling with cyanobenzothiazole conjugates | Promega Corporation (US) | 2013-08-14 | — | — | EP | disclosed |
| US-20090263843-A1 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2009-10-22 | — | — | US | disclosed |
| US-20090263843-A1 | Protein labeling with cyanobenzothiazole conjugates | PROMEGA CORPORATION (US) | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090263843-A1 | Protein labeling with cyanobenzothiazole conjugates | QPCTL, BCAT1, QPCT | KCNH2 3175/4885JAK2 2574/4885NT5E 1425/4885 |
| US-20170283456-A1 | PROTEIN LABELING WITH CYANOBENZOTHIAZOLE CONJUGATES | QPCTL, BCAT1, QPCT | KCNH2 3175/4885JAK2 2574/4885NT5E 1425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.