SCHEMBL181194

SCHEMBL181194

Clc1ccc([Mg]Br)cc1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23466995 1.00 LMNA (0.50)
Bromide SCHEMBL1272014 0.97 LMNA (0.47)
SCHEMBL11837452 0.92 CYP1A2 (0.48)
SCHEMBL6944008 0.89 TSHR (0.48)
SCHEMBL5487650 0.83
Ether SCHEMBL18264284 0.82 KDM4E (0.39)
SCHEMBL2315951 0.71
SCHEMBL3027928 0.71
1,4-Dichlorobenzene SCHEMBL5191 0.71
1,4-Dichlorobenzene SCHEMBL11243685 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2005 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242747-A1 MULTI -COMPONENT FORMULATIONS OF ORGANOMETALLIC REAGENTS MERCK PATENT GMBH (DE) 2025-11-27 WO claimed
CN-119591483-A Synthesis method of (4-chlorophenyl) (4-hydroxy-3, 5-dimethoxy phenyl) methanone 广东莱佛士制药技术有限公司 2025-03-11 CN claimed
CN-118874435-A Preparation method of macroporous adsorption resin for waste gas treatment 蚌埠市天星树脂有限责任公司 2024-11-01 CN claimed
CN-118125969-A Haloperidol with excellent biological performance and preparation method and application thereof 湖南洞庭药业股份有限公司 2024-06-04 CN claimed
CN-117164419-A Chiral synthesis method of bestatin intermediate 江苏联环药业股份有限公司 2023-12-05 CN claimed
CN-113620869-B Preparation method of betrixaban 江西同和药业股份有限公司 2023-04-18 CN claimed
CN-113620869-A Preparation method of betrixaban 江西同和药业股份有限公司 2021-11-09 CN claimed
CN-112538042-A Preparation method of haloperidol 湖南洞庭药业股份有限公司 2021-03-23 CN claimed
CN-108503652-A A kind of fully synthetic preparation method of chemistry of crotons alkane diterpene Prostratin 西安交通大学 2018-09-07 CN claimed
CN-108017549-A A kind of preparation method of 1- aryl -2- amino -1,3- propanediol hydrochloride derivatives 南通常佑药业科技有限公司 2018-05-11 CN claimed
CN-1962657-A 2-beta- carbomethoxy-3 beta-(4- chlorphenyl) tropane synthesis method JIANGSU INST OF NUCLEAR MED (CN) 2007-05-16 CN claimed
EP-1594824-A4 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF ATHEROGENICS INC (US) 2007-04-04 EP claimed
EP-1594824-A2 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF Atherogenics, Inc. (US) 2005-11-16 EP claimed
US-20040204485-A1 Process of preparing esters and ethers of probucol and derivatives thereof CRABTREE ACQUISITION CO, LLC 2004-10-14 US claimed
WO-2004062622-A2 PROCESS OF PREPARING ESTERS AND ETHERS OF PROBUCOL AND DERIVATIVES THEREOF ATHEROGENICS, INC. (US) 2004-07-29 WO claimed
EP-1120397-A2 Process for preparing triazole derivative KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2001-08-01 EP claimed
EP-1064286-A1 SYNTHESIS OF ARYL BORONIC ACIDS BOULDER SCIENTIFIC COMPANY (US) 2001-01-03 EP claimed
WO-1999064428-A1 SYNTHESIS OF ARYL BORONIC ACIDS BOULDER SCIENTIFIC COMPANY (US) 1999-12-16 WO claimed
EP-0704419-A1 PROCESS FOR PRODUCING TRIAZOLE DERIVATIVE KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1996-04-03 EP claimed
US-4902833-A Bisphosphine dioxides UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-02-20 US claimed