Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 6/20 | 0.83 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.61 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.61 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.61 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.61 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.61 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.61 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | RORC | P51449 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1057407 | 0.87 | SPPL2A (0.85) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1058746 | 0.87 | SPPL2A (0.81) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4911140 | 0.84 | SPPL2A (0.76) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL4373559 | 0.84 | SPPL2A (0.76) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL14338808 | 0.83 | SPPL2A (0.76) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL1056509 | 0.83 | SPPL2A (0.75) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5780154 | 0.83 | SPPL2A (0.75) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL5778426 | 0.83 | SPPL2A (0.75) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL23129692 | 0.83 | SPPL2A (0.74) | SPPL2APSEN1PSEN2APH1BNCSTN | |
| SCHEMBL9605440 | 0.83 | SPPL2A (0.74) | SPPL2APSEN1PSEN2APH1BNCSTN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061590-A1 | NOVEL CARBOXAMIDE DERIVATIVES AS HIV INHIBITORS | HETERO RESEARCH FOUNDATION (IN) | 2011-05-26 | — | — | WO | disclosed |