Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPPL2A | Q8TCT8 | 3/20 | 0.74 |
| ▸ | MLNR | O43193 | 1/20 | 0.57 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CTSD | P07339 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.57 |
| ▸ | CNR1 | P21554 | 1/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.53 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.53 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.53 |
| ▸ | KCND3 | Q9UK17 | 1/20 | 0.53 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.53 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.53 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.53 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL608142 | 1.00 | SPPL2A (0.74) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1051190 | 1.00 | SPPL2A (0.74) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL10031792 | 1.00 | SPPL2A (0.74) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL23129692 | 1.00 | SPPL2A (0.74) | SPPL2AMLNRABCB11LMNACTSD | |
| Hydrochloric Acid SCHEMBL14637729 | 0.99 | SPPL2A (0.73) | SPPL2AMLNRABCB11LMNACTSD | |
| Hydrochloric Acid SCHEMBL14636197 | 0.99 | SPPL2A (0.73) | SPPL2AMLNRABCB11LMNACTSD | |
| Sulfuric Acid SCHEMBL18281506 | 0.98 | SPPL2A (0.72) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL4373559 | 0.94 | SPPL2A (0.76) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL4911140 | 0.94 | SPPL2A (0.76) | SPPL2AMLNRABCB11LMNACTSD | |
| SCHEMBL1054059 | 0.92 | SPPL2A (0.73) | SPPL2AMLNRABCB11LMNACTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2643326-B1 | Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro[2,3-b]furan-3-ol | MYLAN LAB LTD (IN) | 2016-09-14 | — | — | EP | disclosed |
| US-8841467-B2 | Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro [2, 3-b] furan-3-ol | MYLAN LABORATORIES LIMITED (IN) | 2014-09-23 | — | — | US | disclosed |
| US-8841467-B2 | Process for the preparation of (3R, 3aS, 6aR)-hexahydrofuro [2, 3-b] furan-3-ol | MYLAN LABORATORIES LIMITED (IN) | 2014-09-23 | — | — | US | disclosed |
| US-20130244297-A1 | PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B] FURAN-3-OL | Mylan Laboratories Ltd. (IN) | 2013-09-19 | — | — | US | disclosed |
| US-20130244297-A1 | PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B] FURAN-3-OL | Mylan Laboratories Ltd. (IN) | 2013-09-19 | — | — | US | disclosed |
| WO-2012070057-A1 | PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B] FURAN-3-OL | MATRIX LABORATORIES LTD (IN) | 2012-05-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130244297-A1 | PROCESS FOR THE PREPARATION OF (3R, 3AS, 6AR)-HEXAHYDROFURO [2, 3- B] FURAN-3-OL | HPD, HAAO, DHRS9 | SPPL2A 2165/4885MLNR 4490/4885ABCB11 2433/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.