SCHEMBL1812072

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	Hydrochloric Acid SCHEMBL1811060	0.99	WNK1 (0.54)	WNK1MAPTTDP1POLBCA12
	SCHEMBL1700017	0.93	MAPT (0.50)	WNK1MAPTTDP1POLBCA12
	SCHEMBL1700282	0.93	MAPT (0.50)	WNK1MAPTTDP1POLBCA12
	Tert-Butyl Formate SCHEMBL27935376	0.88	MAPT (0.48)	WNK1MAPTTDP1POLBCA12
	SCHEMBL1542018	0.87	WNK1 (0.70)	WNK1MAPTTDP1POLBHCAR3
	SCHEMBL1700655	0.87	MAPT (0.54)	WNK1MAPTTDP1POLBCA12
	SCHEMBL30467953	0.87	MAPT (0.54)	WNK1MAPTTDP1POLBCA12
	SCHEMBL2387562	0.86	WNK1 (0.59)	WNK1MAPTTDP1POLBCA12
	Hydrochloric Acid SCHEMBL2480333	0.85	MAPT (0.44)	WNK1MAPTTDP1POLBGAA
	SCHEMBL1700242	0.83	MAPT (0.47)	WNK1MAPTPOLBCA12CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 101 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (12 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.