SCHEMBL1812224

SCHEMBL1812224

O=C1NC(=S)SC1=Cc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NAT1 P18440 7/20 1.00
CA2 P00918 1/20 1.00
EPHX1 P07099 1/20 1.00
MMP3 P08254 2/20 0.75
MMP13 P45452 2/20 0.75
PIM1 P11309 2/20 0.71
PIM3 Q86V86 1/20 0.71
PIM2 Q9P1W9 1/20 0.71
CISD1 Q9NZ45 4/20 0.71
MYC P01106 2/20 0.71
MAOA P21397 1/20 0.71
MAX P61244 1/20 0.71
IL1RN P18510 1/20 0.69
ERAP1 Q9NZ08 1/20 0.69
MEN1 O00255 1/20 0.68
RAB9A P51151 1/20 0.68
KMT2A Q03164 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3491175 1.00 NAT1 (1.00) NAT1CA2EPHX1MMP3MMP13
SCHEMBL4416451 1.00 NAT1 (1.00) NAT1CA2EPHX1MMP3MMP13
SCHEMBL1247510 0.90 NAT1 (1.00) NAT1CA2EPHX1MMP3MMP13
SCHEMBL10596480 0.90 NAT1 (1.00) NAT1CA2EPHX1MMP3MMP13
SCHEMBL1247509 0.90 NAT1 (1.00) NAT1CA2EPHX1MMP3MMP13
SCHEMBL8173568 0.86 NAT1 (0.75) NAT1CA2EPHX1MMP3MMP13
SCHEMBL18103088 0.86 MMP3 (1.00) NAT1CA2EPHX1MMP3MMP13
SCHEMBL18102890 0.86 NAT1 (0.76) NAT1CA2EPHX1MMP3MMP13
SCHEMBL8173565 0.86 NAT1 (0.75) NAT1CA2EPHX1MMP3MMP13
SCHEMBL19991267 0.86 NAT1 (0.76) NAT1CA2EPHX1MMP3MMP13

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0343643-A2 Arylmethylenyl derivatives of thiazolidnones, imidazolidinones and oxazolidinones useful as antiallergy agents and antiinflamatory agents WARNER-LAMBERT COMPANY (US) 1989-11-29 EP claimed
EP-3102193-B1 ANTIBACTERIAL AGENTS: N(ALPHA)-AROYL-N-ARYL-PHENYLALANINAMIDES UNIV RUTGERS (US) 2023-01-11 EP disclosed
CN-110078733-B Double-functionalized alkaline ionic liquid catalyst and preparation method and application thereof 中国科学院兰州化学物理研究所苏州研究院 2020-07-24 CN disclosed
CN-110078733-A One kind difunctionalization alkaline ionic liquid catalyst and the preparation method and application thereof 中国科学院兰州化学物理研究所苏州研究院 2019-08-02 CN disclosed
CN-103443072-B Polymerizable composition comprising oxime sulfonate as thermal curing agent BASF SE (DE) 2016-05-18 CN disclosed
US-8431376-B2 Bacterial replication systems and methods THE REGENTS OF THE UNIVERSITY OF COLORADO (US) 2013-04-30 US disclosed
CN-102058585-B Application of Rhodanine derivates as antineoplastic medicine UNIV SOOCHOW 2012-11-14 CN disclosed
CN-102741758-A Charge controlling agent and toner using same HODOGAYA CHEMICAL CO LTD 2012-10-17 CN disclosed
CN-101367775-B Rhodanine derivant, preparation method and uses thereof SUZHOU UNIVERSITY (CN) 2011-11-30 CN disclosed
CN-102058585-A Application of Rhodanine derivates as antineoplastic medicine UNIV SUZHOU 2011-05-18 CN disclosed
EP-0658802-A2 Surface latent image type photographic material containing silver halide grains doped with cyano-chromium-complex ion FUJI PHOTO FILM CO., LTD. (JP) 1995-06-21 EP disclosed
US-5389658-A Administering as antipyretic, antiinflammatory, analgesic, antiallergic, or immunosupressive agents TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-02-14 US disclosed
EP-0612729-A2 Pyridine derivatives, their production and use Takeda Chemical Industries, Ltd. (JP) 1994-08-31 EP disclosed
CN-1091006-A Chemical compound as blood sugar lowering and treatment degenerative brain disorder LILLY CO ELI (US) 1994-08-24 CN disclosed
EP-0587377-A2 Thiazolidinone derivatives as hypoglycemic agents and for treating Alzheimer's disease ELI LILLY AND COMPANY (US) 1994-03-16 EP disclosed
US-5266457-A Phosphine sulfide as sensitizer FUJI PHOTO FILM CO., LTD. (JP) 1993-11-30 US disclosed
US-5246948-A Antiinflammatory, antipyretic, analgesic, antiallergic, immunosupressing or immunomodulating activity TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-09-21 US disclosed
EP-0522606-A2 Pyridine derivatives, their production and use TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1993-01-13 EP disclosed
US-4018891-A INHIBITORS OF ANTIGEN-ANTIBODY REACTIONS RICHARDSON-MERRELL INC. (US) 1977-04-19 US disclosed
US-3960892-A ANTIGEN-ANTIBODY REACTION INHIBITION RICHARDSON-MERRELL INC. (US) 1976-06-01 US disclosed