Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 15/20 | 0.35 |
| ▸ | PTGER2 | P43116 | 13/20 | 0.35 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18123909 | 1.00 | PTGER4 (0.35) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL18123906 | 1.00 | PTGER4 (0.35) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL15551554 | 0.79 | PTGER4 (0.44) | PTGER4PTGER2PTGER3 | |
| SCHEMBL17534886 | 0.78 | PTGER4 (0.49) | PTGER4PTGER2PTGER3 | |
| SCHEMBL17534885 | 0.78 | PTGER4 (0.49) | PTGER4PTGER2PTGER3 | |
| SCHEMBL16408738 | 0.78 | NPC1 (0.34) | PTGER4PTGER2 | |
| SCHEMBL18123905 | 0.77 | PTGER4 (0.38) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL18123904 | 0.77 | PTGER4 (0.38) | PTGER4PTGER2PTGER3KCNH2 | |
| SCHEMBL16819443 | 0.74 | PTGER4 (0.44) | PTGER4PTGER2 | |
| SCHEMBL22024693 | 0.74 | PTGER4 (0.44) | PTGER4PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2874620-B1 | DIFLUOROLACTAM COMPOSITIONS FOR EP4-MEDIATED OSTEO RELATED DISEASES AND CONDITIONS | CAYMAN CHEMICAL CO INC (US) | 2016-10-12 | — | — | EP | disclosed |