SCHEMBL18124

SCHEMBL18124

Nc1cc([N+](=O)[O-])cc([N+](=O)[O-])c1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 5/20 1.00
ALDH1A1 P00352 5/20 0.66
TDP1 Q9NUW8 2/20 0.66
HPGD P15428 2/20 0.66
MAPK1 P28482 2/20 0.66
KDM4E B2RXH2 1/20 0.66
MEN1 O00255 1/20 0.66
TTR P02766 1/20 0.66
CYP1A2 P05177 1/20 0.66
MAPT P10636 1/20 0.66
CYP2C9 P11712 1/20 0.66
ALOX15 P16050 1/20 0.66
ALOX12 P18054 1/20 0.66
RECQL P46063 1/20 0.66
PMP22 Q01453 1/20 0.66
KMT2A Q03164 1/20 0.66
HIF1A Q16665 1/20 0.66
HSD17B10 Q99714 1/20 0.66
CA9 Q16790 4/20 0.61
CA1 P00915 4/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29375698 1.00 GPR35 (1.00) GPR35ALDH1A1TDP1HPGDMAPK1
SCHEMBL5439726 0.98 GPR35 (0.96) GPR35ALDH1A1TDP1HPGDMAPK1
SCHEMBL5439731 0.98 GPR35 (0.96) GPR35ALDH1A1TDP1HPGDMAPK1
SCHEMBL8664793 0.88 GPR35 (0.78) GPR35ALDH1A1TDP1HPGDMAPK1
SCHEMBL10883008 0.87 GPR35 (0.77) GPR35ALDH1A1TDP1HPGDMAPK1
Trinitrophenol SCHEMBL597738 0.87 GPR35 (0.77) GPR35ALDH1A1TDP1HPGDMAPK1
Trinitrophenol SCHEMBL23496617 0.85 GPR35 (0.74) GPR35ALDH1A1TDP1HPGDMAPK1
Trinitrophenol SCHEMBL9141134 0.85 GPR35 (0.74) GPR35ALDH1A1TDP1HPGDMAPK1
Trinitrophenol SCHEMBL253750 0.85 GPR35 (0.79) GPR35ALDH1A1TDP1HPGDMAPK1
Trinitrophenol SCHEMBL8744 0.85 GPR35 (0.79) GPR35ALDH1A1TDP1HPGDMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 5853 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723864-B1 THICKENED ONE-COMPONENT HAIR TONER HENKEL AG & CO KGAA (DE) 2026-01-14 EP claimed
EP-4658168-A2 METHOD FOR IMPROVED SENSOR SENSITIVITY OF A MICRONEEDLE-BASED CONTINUOUS ANALYTE MONITORING SYSTEM Biolinq, Inc. (US) 2025-12-10 EP claimed
US-12383478-B2 Cosmetic product for dyeing keratin fibers KAO CORPORATION (JP) 2025-08-12 US claimed
US-12364660-B2 Granulated hair dye composition WELLA GERMANY GMBH (DE) 2025-07-22 US claimed
EP-3873407-B1 TWO-COMPONENT SYSTEM FOR ARTIFICIAL HAIR DYEING HENKEL AG & CO KGAA (DE) 2025-04-09 EP claimed
WO-2025061335-A1 METHOD FOR DYEING KERATIN FIBRES, COMPRISING THE APPLICATION OF AN OXIDATIVE PRE-TREATMENT AGENT AND A DYE COMPRISING DIRECT DYES HENKEL AG & CO. KGAA (DE) 2025-03-27 WO claimed
US-20240423887-A1 COMPOSITION COMPRISING A DYE AND INORGANIC ALKALIZING AGENT KAO CORPORATION (JP) 2024-12-26 US claimed
US-20240350386-A1 Hair Coloring Compositions Comprising Hydroxyalkyl Amines As Alkalising Agents WELLA GERMANY GMBH (DE) 2024-10-24 US claimed
US-20240315614-A1 METHOD FOR IMPROVED SENSOR SENSITIVITY OF A MICRONEEDLE-BASED CONTINUOUS ANALYTE MONITORING SYSTEM BIOLINQ INCORPORATED 2024-09-26 US claimed
EP-4247323-B1 GRANULATED HAIR DYE COMPOSITION WELLA GERMANY GMBH (DE) 2024-09-04 EP claimed
EP-0166155-B1 2-ALKYLSULPHONYL-1,4-DIAMINOBENZENES, PROCESS FOR THEIR PREPARATION AND OXIDATIVE HAIR-DYEING COMPOSITIONS CONTAINING THESE COMPOUNDS Wella Aktiengesellschaft (DE) 1987-09-23 EP claimed
EP-0226072-A1 Oxidation dye containing 4-amino-2-aminomethyl phenol Wella Aktiengesellschaft (DE) 1987-06-24 EP claimed
WO-1987003475-A2 OXIDIZING HAIR DYER BASED ON 4-AMINO-2-AMINOMETHYLPHENOLS WELLA AKTIENGESELLSCHAFT (DE) 1987-06-18 WO claimed
CN-85103112-A Oxide hair dye based on the low viscosity carrier material 1986-10-22 CN claimed
WO-1986000223-A1 HAIR COLOURING AGENT BASED ON A LOW-VISCOSITY CARRIER WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO claimed
WO-1986000303-A1 TWO-ALKYL-SULPHONYL-1,4-DIAMINOBENZENES, PREPARATION THEREOF AND UTILISATION THEREOF WELLA AKTIENGESELLSCHAFT (DE) 1986-01-16 WO claimed
EP-0166155-A1 2-Alkylsulphonyl-1,4-diaminobenzenes, process for their preparation and oxidative hair-dyeing compositions containing these compounds Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed
EP-0166100-A1 Oxidation hair-dyeing composition based on a low-viscosity carrier Wella Aktiengesellschaft (DE) 1986-01-02 EP claimed
US-4543425-A 1,3-Diamino-4-(2',2',2',-trifluoroethoxy)-benzene, method of producing the same, and hair coloring composition containing the same WELLA AG (DE) 1985-09-24 US claimed
WO-1983001771-A1 DERIVATIVES OF 2-HYDROXY-4-AMINO-BENZENE, PREPARATION THEREOF AND HAIR DYE CONTAINING SUCH DERIVATIVES KONRAD, EUGEN 1983-05-26 WO claimed