Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Trinitrophenol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 11/20 | 0.79 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.79 |
| ▸ | HPGD | P15428 | 2/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.79 |
| ▸ | MEN1 | O00255 | 2/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.79 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.79 |
| ▸ | TTR | P02766 | 1/20 | 0.79 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.79 |
| ▸ | MAPT | P10636 | 1/20 | 0.79 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.79 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.79 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.79 |
| ▸ | RECQL | P46063 | 1/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.79 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.79 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.79 |
| ▸ | TP53 | P04637 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL253750 | 1.00 | GPR35 (0.79) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL18691159 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL1692116 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL9641273 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL2197458 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL1503376 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL2260890 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL9140811 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL2218625 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 | |
| Trinitrophenol SCHEMBL11746249 | 0.98 | GPR35 (0.76) | GPR35ALDH1A1HPGDMAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 116652 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026107510-A1 | HOT-MELT ADHESIVE COMPOSITION AND METHOD OF APPLICATION | BIOBOND ADHESIVES, INC. (US) | 2026-05-21 | — | — | WO | claimed |
| EP-4746100-A1 | COMPOSITION FOR GEL POLYMER ELECTROLYTE, GEL POLYMER ELECTROLYTE, AND LITHIUM SECONDARY BATTERY COMPRISING GEL POLYMER ELECTROLYTE | SK On Co., Ltd. (KR) | 2026-05-20 | — | — | EP | claimed |
| EP-4745135-A1 | COMPOUND BASED ON THIO-GLUTARIMIDO ISOINDOLINONE SKELETON AND USE THEREOF | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | claimed |
| EP-4745137-A1 | GLUTARIMIDE ISOINDOLINONE SKELETON-BASED COMPOUND | Gluetacs Therapeutics (Shanghai) Co., Ltd. (CN) | 2026-05-20 | — | — | EP | claimed |
| CN-122070479-A | Ultrasonic indicating device and method for monitoring ultrasonic treatment | JP实验室股份有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-12629358-B2 | Compound used as RET kinase inhibitor and application thereof | TYK MEDICINES, INC. (CN) | 2026-05-19 | — | — | US | claimed |
| CN-122070278-A | Bifunctional protein degradation agent containing aryl substituted heteroaryl and application thereof | 标新生物医药科技(上海)有限公司 | 2026-05-19 | — | — | CN | claimed |
| US-12630551-B2 | Endocyclic pyrimidinone compounds, and preparation methods, compositions and use thereof | NEUSCO BIOTECH LIMITED (CN) | 2026-05-19 | — | — | US | claimed |
| CN-122036715-A | 2, 4-Diarylaminopyrimidine derivative containing benzodithioryl, and pharmaceutical composition and application thereof | 盐城工业职业技术学院 | 2026-05-15 | — | — | CN | claimed |
| CN-122055148-A | Conjugates, compositions and methods for treating influenza | 珀杜研究基金会 | 2026-05-15 | — | — | CN | claimed |
| US-3999989-A | SALTS OF INDOLINE SPIROBENZOPYRANS | FUJI PHOTO FILM CO., LTD. (JA) | 1976-12-28 | — | — | US | claimed |
| US-3982938-A | Photoconductive toners which include photoconductive pigment particles in a charge-transporting insulating binder | FUJI PHOTO FILM CO., LTD. (JA) | 1976-09-28 | — | — | US | claimed |
| US-3957550-A | EXPLOSIVES, LIQUID FUELS, OXIDIZERS | THIOKOL CORPORATION (US) | 1976-05-18 | — | — | US | claimed |
| US-3953297-A | Determination of amylase | PIERCE CHEMICAL COMPANY (US) | 1976-04-27 | — | — | US | claimed |
| US-3953577-A | Process for purifying gases containing HCN | OSAKA GAS COMPANY, LIMITED (JA) | 1976-04-27 | — | — | US | claimed |
| US-3953259-A | PROPELLANTS, HEXANITRO-STILBENE, TRIAMINO-TRINITROBENZENE, PICRIC ACID | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 1976-04-27 | — | — | US | claimed |
| US-3951984-A | 3-Benzazocine compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-04-20 | — | — | US | claimed |
| US-3936447-A | 7-Acylamino-desacetoxy-cephalosporanic acid esters and their production | BAYER AKTIENGESELLSCHAFT (DT) | 1976-02-03 | — | — | US | claimed |
| US-3933509-A | Photo-polymerizable composition containing an acid salt of an indolinobenzospiropyran | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-20 | — | — | US | claimed |
| US-3931552-A | Capacitor electrolyte | P. R. MALLORY & CO., INC. (US) | 1976-01-06 | — | — | US | claimed |