⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2300931 | 0.74 | — | — | |
| SCHEMBL4668194 | 0.64 | — | — | |
| SCHEMBL5478554 | 0.64 | — | — | |
| SCHEMBL1811649 | 0.62 | LMNA (0.46) | — | |
| SCHEMBL2346044 | 0.62 | ALDH1A1 (0.46) | — | |
| SCHEMBL20448755 | 0.62 | — | — | |
| SCHEMBL2322085 | 0.60 | ALDH1A1 (0.44) | — | |
| SCHEMBL6398085 | 0.54 | — | — | |
| SCHEMBL12009472 | 0.54 | — | — | |
| SCHEMBL28980 | 0.54 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100234396-A1 | Tetrhydropyridoindole Derivatives | ACTELION PHARMACEUTICALS LTD (CH) | 2010-09-16 | — | — | US | claimed |
| EP-2056897-B1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES B V (NL) | 2009-12-30 | — | — | EP | claimed |
| EP-1723140-B1 | PROCESS FOR THE PREPARATION OF TRYPTASE INHIBITORS | AVENTIS PHARMA INC (US) | 2009-11-04 | — | — | EP | claimed |
| US-20090258053-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEEVICES BV (NL) | 2009-10-15 | — | — | US | claimed |
| EP-2056897-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | Blue Medical Devices B.V. (NL) | 2009-05-13 | — | — | EP | claimed |
| EP-1725553-B1 | TETRAHYDROPYRIDOINDOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2008-05-07 | — | — | EP | claimed |
| US-20080050413-A1 | Medical stent provided with a combination of melatonin and paclitaxel | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | US | claimed |
| WO-2008023038-A1 | MEDICAL STENT PROVIDED WITH A COMBINATION OF MELATONIN AND PACLITAXEL | BLUE MEDICAL DEVICES BV (NL) | 2008-02-28 | — | — | WO | claimed |
| US-20070191416-A1 | Tetrahydropyridoindole derivatives | IDORSIA PHARMACEUTICALS LTD (CH) | 2007-08-16 | — | — | US | claimed |
| EP-1725553-A1 | TETRAHYDROPYRIDOINDOLE DERIVATIVES | Actelion Pharmaceuticals Ltd. (CH) | 2006-11-29 | — | — | EP | claimed |
| WO-2005105843-A2 | HIV PROTEASE INHIBITORS | ARPIDA A/S (DK) | 2005-11-10 | — | — | WO | claimed |
| WO-2005095397-A1 | TETRAHYDROPYRIDOINDOLE DERIVATIVES | ACTELION PHARMACEUTICALS LTD (CH) | 2005-10-13 | — | — | WO | claimed |
| US-5179107-A | Herpes | SCHERING CORPORATION (US) | 1993-01-12 | — | — | US | claimed |
| US-20230346960-A1 | PROTEOGLYCAN MIMETICS FOR ENHANCED WOUND HEALING, ANGIOGENESIS, AND VASCULAR REPAIR | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-11-02 | — | — | US | disclosed |
| US-11612663-B2 | Proteoglycan mimetics for enhanced wound healing, angiogenesis, and vascular repair | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2023-03-28 | — | — | US | disclosed |
| CN-109196004-B | Engineered scaffold for vascularized tissue repair | 加利福尼亚大学董事会 | 2022-03-18 | — | — | CN | disclosed |
| US-6020342-A | Fused imidazo[1,2-A]pyridines | SHINNIPPON PHARMACEUTICAL, INC. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0822194-A1 | FUSED IMIDAZO 1,2-a]PYRIDINES | Shinnippon Pharmaceutical Inc. (JP) | 1998-02-04 | — | — | EP | disclosed |
| US-5190956-A | Certain N-substituted 3-oximino-2,4-dioxoquinolin-2,4-(1H)diones useful for treating viral infections | SCHERING CORPORATION (US) | 1993-03-02 | — | — | US | disclosed |
| US-5179107-A | Herpes | SCHERING CORPORATION (US) | 1993-01-12 | — | — | US | disclosed |