SCHEMBL18179380

SCHEMBL18179380

C[Si](C)(C)O[Si](O[Si](C)(C)c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.34
ESR2 Q92731 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11434022 0.93 ESR1 (0.38) ESR1ESR2
SCHEMBL29032529 0.91 ESR1 (0.37) ESR1ESR2
SCHEMBL30003065 0.91 ESR1 (0.37) ESR1ESR2
SCHEMBL94228 0.91 ESR1 (0.39) ESR1ESR2
SCHEMBL12977053 0.91 LMNA (0.34) ESR1ESR2
SCHEMBL16521498 0.89 ESR1 (0.38) ESR1ESR2
SCHEMBL8992173 0.89 ESR1 (0.38) ESR1ESR2
SCHEMBL18125 0.86 ESR1 (0.39) ESR1ESR2
SCHEMBL26973343 0.85 ESR1 (0.33) ESR1ESR2
SCHEMBL30002398 0.83 ESR1 (0.32) ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9789035-B2 Lip composition in the form of an inverse emulsion comprising a humectant, and treatment process using the same L'OREAL (FR) 2017-10-17 US disclosed
US-9789035-B2 Lip composition in the form of an inverse emulsion comprising a humectant, and treatment process using the same L'OREAL (FR) 2017-10-17 US disclosed
US-20170216183-A1 EMULSION COMPRISING A SILICONE-BASED DENDRITIC FILM-FORMING POLYMER AND A SILICONE GUM, TREATMENT PROCESS USING THE SAME AND SUITABLE DEVICE L'OREAL (FR) 2017-08-03 US disclosed
US-20160310374-A1 LIP COMPOSITION IN THE FORM OF AN INVERSE EMULSION COMPRISING A HUMECTANT, AND TREATMENT PROCESS USING THE SAME L'OREAL (FR) 2016-10-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160310374-A1 LIP COMPOSITION IN THE FORM OF AN INVERSE EMULSION COMPRISING A HUMECTANT, AND TREATMENT PROCESS USING THE SAME LIPA, LIPE, LIPC ESR1 2105/4885ESR2 2462/4885
US-20170216183-A1 EMULSION COMPRISING A SILICONE-BASED DENDRITIC FILM-FORMING POLYMER AND A SILICONE GUM, TREATMENT PROCESS USING THE SAME AND SUITABLE DEVICE TLR9, TLR3, TLR7 ESR1 3993/4885ESR2 4527/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.