Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 3/20 | 0.43 |
| ▸ | NNMT | P40261 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 1/20 | 0.37 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.33 |
| ▸ | P4HA1 | P13674 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1793716 | 0.85 | CXCR4 (0.53) | CXCR4SMN1; SMN2KLK1KLK5TAAR1 | |
| SCHEMBL1811130 | 0.84 | CXCR4 (0.39) | CXCR4SMN1; SMN2TAAR1CYP2D6TSHR | |
| SCHEMBL1810039 | 0.83 | CXCR4 (0.41) | CXCR4NNMTSMN1; SMN2KLK1KLK5 | |
| SCHEMBL1794404 | 0.78 | CXCR4 (0.44) | CXCR4SMN1; SMN2KDM4ETAAR1CYP2D6 | |
| SCHEMBL840090 | 0.75 | NNMT (0.45) | NNMTSMN1; SMN2KDM4EL3MBTL1TSHR | |
| SCHEMBL4607724 | 0.75 | CXCR4 (0.47) | CXCR4KDM4E | |
| SCHEMBL1808509 | 0.75 | CXCR4 (0.41) | CXCR4SMN1; SMN2KLK1KLK5TAAR1 | |
| SCHEMBL1810957 | 0.74 | CXCR4 (0.45) | CXCR4SMN1; SMN2TAAR1CYP2D6TSHR | |
| SCHEMBL1807966 | 0.74 | CXCR4 (0.40) | CXCR4SMN1; SMN2KLK1KLK5TAAR1 | |
| SCHEMBL14856665 | 0.74 | TAAR1 (0.53) | CXCR4SMN1; SMN2KDM4ETAAR1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110142856-A1 | COMPOUND CONTAINING BASIC GROUP AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-06-16 | — | — | US | disclosed |
| US-7951816-B2 | Compound containing basic group and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2011-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110142856-A1 | COMPOUND CONTAINING BASIC GROUP AND USE THEREOF | CXCR4, CCR5, CXCL12 | CXCR4 1/4885NNMT 92/4885SMN1; SMN2 1481/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.