Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | IDH1 | O75874 | 3/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18114398 | 0.81 | SLC6A2 (0.46) | KMT2ASLC6A2SLC6A4SLC6A3HDAC2 | |
| SCHEMBL18127406 | 0.81 | SLC6A2 (0.46) | KMT2ASLC6A2SLC6A4SLC6A3HDAC2 | |
| SCHEMBL3015928 | 0.77 | SLC6A2 (0.49) | OPRK1SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL18127121 | 0.75 | KDM4E (0.40) | NPC1ALDH1A1RAB9AKMT2AHDAC2 | |
| SCHEMBL18127118 | 0.75 | MEN1 (0.46) | ALDH1A1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18127393 | 0.75 | ERCC5 (0.39) | NPC1ALDH1A1RAB9AKMT2ASLC6A2 | |
| SCHEMBL18127404 | 0.73 | SLC6A2 (0.39) | ALDH1A1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18126990 | 0.73 | SLC6A2 (0.39) | SLC6A2SLC6A4SLC6A3HDAC2HDAC8 | |
| SCHEMBL18127123 | 0.73 | MEN1 (0.44) | ALDH1A1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18127392 | 0.73 | GRM5 (0.42) | ALDH1A1KMT2ASLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016160677-A1 | COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2016-10-06 | — | — | WO | disclosed |