Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC5 | P28715 | 2/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18114398 | 0.79 | SLC6A2 (0.46) | GAAHCRTR1HCRTR2SLC6A2SLC6A4 | |
| SCHEMBL18127406 | 0.79 | SLC6A2 (0.46) | GAAHCRTR1HCRTR2SLC6A2SLC6A4 | |
| SCHEMBL18127116 | 0.77 | SMN1; SMN2 (0.47) | DRD4DRD3ALDH1A1KDM4EHPGD | |
| SCHEMBL18127114 | 0.75 | OPRK1 (0.42) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18127404 | 0.73 | SLC6A2 (0.39) | ALDH1A1KDM4ESLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18127118 | 0.72 | MEN1 (0.46) | ALDH1A1KDM4EHCRTR1HCRTR2SLC6A2 | |
| SCHEMBL18126990 | 0.71 | SLC6A2 (0.39) | HCRTR1HCRTR2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18127123 | 0.71 | MEN1 (0.44) | DRD4DRD3ALDH1A1KDM4ESLC6A2 | |
| SCHEMBL18127121 | 0.71 | KDM4E (0.40) | ALDH1A1KDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL18127392 | 0.70 | GRM5 (0.42) | ALDH1A1KDM4EHPGDGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016160677-A1 | COMPOUNDS FOR THE TREATMENT OF ARENAVIRUS INFECTION | ARISAN THERAPEUTICS INC. (US) | 2016-10-06 | — | — | WO | disclosed |