Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 2/20 | 0.41 |
| ▸ | LOXL2 | Q9Y4K0 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17608918 | 0.82 | PDE2A (0.49) | POLBMAPK1ALDH1A1HTTBRD4 | |
| SCHEMBL18129000 | 0.79 | SMN1; SMN2 (0.43) | CYP1A2CYP2C9CYP2C19MAPTNPSR1 | |
| SCHEMBL18128983 | 0.79 | SRD5A2 (0.44) | CYP1A2CYP2C9CYP2C19MAPTNPSR1 | |
| SCHEMBL18951960 | 0.78 | MEN1 (0.50) | CYP1A2CYP2C9CYP2C19MAPTNPSR1 | |
| SCHEMBL18128984 | 0.77 | CYP1A2 (0.44) | CYP1A2CYP2C9CYP2C19MAPTMAPK1 | |
| SCHEMBL18951928 | 0.76 | BCAT2 (0.50) | CYP1A2CYP2C9CYP2C19MAPTCYP3A4 | |
| SCHEMBL3404366 | 0.75 | ALDH1A1 (0.53) | CYP2C19POLBCYP3A4TDP1ALDH1A1 | |
| SCHEMBL446237 | 0.75 | MAPT (0.63) | CYP1A2CYP2C9CYP2C19MAPTNPSR1 | |
| SCHEMBL12582151 | 0.74 | ALDH1A1 (0.43) | CYP1A2CYP2C9CYP2C19MAPTNPSR1 | |
| SCHEMBL24309569 | 0.73 | TDP1 (0.70) | CYP1A2CYP2C9CYP2C19MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9796677-B2 | Amide compound and pharmaceutical comprising same | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2017-10-24 | — | — | US | disclosed |
| EP-3081556-A1 | AMIDE COMPOUND AND PHARMACEUTICAL COMPRISING SAME | Japan Science and Technology Agency (JP) | 2016-10-19 | — | — | EP | disclosed |
| US-20160297764-A1 | AMIDE COMPOUND AND PHARMACEUTICAL COMPRISING SAME | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297764-A1 | AMIDE COMPOUND AND PHARMACEUTICAL COMPRISING SAME | APP, BACE1, APBA1 | CYP1A2 1408/4885CYP2C9 940/4885CYP2C19 1578/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.