Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR183 | P32249 | 1/20 | 0.65 |
| ▸ | NPC1 | O15118 | 1/20 | 0.65 |
| ▸ | HPGD | P15428 | 1/20 | 0.65 |
| ▸ | RAB9A | P51151 | 1/20 | 0.65 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.56 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.56 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1374133 | 0.92 | NPC1 (0.77) | GPR183NPC1HPGDRAB9ATPSAB1 | |
| Trifluoroacetic Acid SCHEMBL5076132 | 0.82 | KDR (0.60) | GPR183NPC1HPGDRAB9ATPSAB1 | |
| Trifluoroacetic Acid SCHEMBL31439548 | 0.82 | TPSAB1 (0.64) | TPSAB1TPSD1TPSG1LMNAMAPT | |
| Trifluoroacetic Acid SCHEMBL31439561 | 0.82 | TPSAB1 (0.64) | GPR183HPGDRAB9ATPSAB1TPSD1 | |
| SCHEMBL5072941 | 0.79 | MEN1 (0.78) | GPR183TPSAB1TPSD1TPSG1LMNA | |
| Hydrochloric Acid SCHEMBL211137 | 0.78 | MEN1 (0.76) | GPR183TPSAB1TPSD1TPSG1LMNA | |
| SCHEMBL31439495 | 0.76 | TPSAB1 (0.70) | HPGDRAB9ATPSAB1TPSD1TPSG1 | |
| SCHEMBL656497 | 0.76 | TPSAB1 (0.70) | HPGDRAB9ATPSAB1TPSD1TPSG1 | |
| SCHEMBL13660395 | 0.75 | TPSAB1 (0.57) | GPR183NPC1HPGDRAB9ATPSAB1 | |
| Trifluoroacetic Acid SCHEMBL25225724 | 0.74 | L3MBTL1 (0.54) | HPGDLMNAMAPTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | CMA1, CHIA, AADAC | GPR183 811/4885NPC1 1689/4885HPGD 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.