SCHEMBL1812974

SCHEMBL1812974

[CH2]CCCCCCCCCCC(C)CCCCC

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACE2 Q9BYF1 1/20 0.52
OPRM1 P35372 1/20 0.44
LMNA P02545 2/20 0.42
SPHK1 Q9NYA1 1/20 0.41
PRKD3 O94806 1/20 0.41
PRKCG P05129 1/20 0.41
PRKCB P05771 1/20 0.41
PRKCA P17252 1/20 0.41
PRKCH P24723 1/20 0.41
PRKCI P41743 1/20 0.41
PRKCE Q02156 1/20 0.41
PRKCQ Q04759 1/20 0.41
PRKCZ Q05513 1/20 0.41
PRKCD Q05655 1/20 0.41
PRKD1 Q15139 1/20 0.41
DNM1 Q05193 2/20 0.40
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
ADH1B P00325 1/20 0.39
ADH1C P00326 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL199331 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL201050 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL201116 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL25178063 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL25186110 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL25181811 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL25185241 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL25185981 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL21219900 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3
SCHEMBL3949790 1.00 ACE2 (0.52) ACE2OPRM1LMNASPHK1PRKD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118201905-A Cationic lipid 武田药品工业株式会社 2024-06-14 CN disclosed
WO-2024018761-A1 NEUTRAL LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2024018762-A1 PH-SENSITIVE CATIONIC LIPID AND LIPID NANOPARTICLE 国立大学法人北海道大学 2024-01-25 WO disclosed
WO-2023085299-A1 CATIONIC LIPID 武田薬品工業株式会社 2023-05-19 WO disclosed
US-10059700-B2 Supported catalyst for aldehyde coupling reaction , method for performing aldehyde coupling reaction, and method for regenerating supported catalyst for aldehyde coupling reaction SEKISUI CHEMICAL CO., LTD. (JP) 2018-08-28 US disclosed
WO-2016195115-A1 SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION, METHOD FOR PERFORMING ALDEHYDE COUPLING REACTION, AND METHOD FOR REGENERATING SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION SEKISUI CHEMICAL CO., LTD. (JP) 2016-12-08 WO disclosed
US-20160346774-A1 SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION , METHOD FOR PERFORMING ALDEHYDE COUPLING REACTION, AND METHOD FOR REGENERATING SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION SEKISUI CHEMICAL CO., LTD. (JP) 2016-12-01 US disclosed
US-20130244984-A1 Ceramide Production Promoter KAO CORPORATION (JP) 2013-09-19 US disclosed
US-8440645-B2 Ceramide production promoter KAO CORPORATION (JP) 2013-05-14 US disclosed
CN-102438629-A Ceramide production promoter KAO CORP 2012-05-02 CN disclosed
US-20110105439-A1 Ceramide Production Promoter KAO CORPORATION (JP) 2011-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110105439-A1 Ceramide Production Promoter CERS2, SPTLC1, SGMS1 ACE2 3943/4885OPRM1 4124/4885LMNA 2210/4885
US-20160346774-A1 SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION , METHOD FOR PERFORMING ALDEHYDE COUPLING REACTION, AND METHOD FOR REGENERATING SUPPORTED CATALYST FOR ALDEHYDE COUPLING REACTION ALDH2, ALDH7A1, ALDH3A1 ACE2 1783/4885OPRM1 4089/4885LMNA 4649/4885
US-20130244984-A1 Ceramide Production Promoter CERS2, SPTLC1, SGMS1 ACE2 3943/4885OPRM1 4124/4885LMNA 2210/4885
US-10059700-B2 Supported catalyst for aldehyde coupling reaction , method for performing aldehyde coupling reaction, and method for regenerating supported catalyst for aldehyde coupling reaction ALDH2, ALDH7A1, ALDH3A1 ACE2 1783/4885OPRM1 4089/4885LMNA 4649/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.