Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.37 |
| ▸ | HTR3B | O95264 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.37 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.37 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18131646 | 1.00 | POLB (0.40) | POLBHTTKDM4EHTR3EHTR3B | |
| SCHEMBL30275298 | 0.88 | POLB (0.38) | POLBHTTKDM4EHTR3EHTR3B | |
| SCHEMBL18131599 | 0.86 | MAOB (0.40) | POLBHTTKDM4EMEN1USP2 | |
| SCHEMBL18131603 | 0.86 | MAOB (0.40) | POLBHTTKDM4EMEN1USP2 | |
| SCHEMBL7750327 | 0.84 | PLK1 (0.41) | POLBKDM4EMEN1KMT2ALMNA | |
| SCHEMBL7750322 | 0.84 | PLK1 (0.41) | POLBKDM4EMEN1KMT2ALMNA | |
| SCHEMBL7747054 | 0.83 | KMT2A (0.54) | POLBHTTKDM4EMEN1KMT2A | |
| SCHEMBL7747051 | 0.83 | KMT2A (0.54) | POLBHTTKDM4EMEN1KMT2A | |
| SCHEMBL7747074 | 0.82 | POLB (0.53) | POLBHTTKDM4EMEN1KMT2A | |
| SCHEMBL7747072 | 0.82 | POLB (0.53) | POLBHTTKDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11337941-B2 | Inhibitors and their uses | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2022-05-24 | — | — | US | claimed |
| EP-3280405-B1 | INHIBITORS AND THEIR USES | RES & INNOVATION UK (GB) | 2021-07-07 | — | — | EP | claimed |
| CN-107709291-B | Inhibitors and uses thereof | 医疗研究局 | 2021-03-12 | — | — | CN | claimed |
| US-20200297668-A1 | INHIBITORS AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2020-09-24 | — | — | US | claimed |
| US-20180125801-A1 | METHODS FOR SELECTING PHOSPHATASE SELECTIVE AND NON-SELECTIVE PHOSPHATASE INHIBITORS | MEDICAL RESEARCH COUNCIL (GB) | 2018-05-10 | — | — | US | claimed |
| US-20180111896-A1 | INHIBITORS AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2018-04-26 | — | — | US | claimed |
| EP-3280405-A1 | INHIBITORS AND THEIR USES | Medical Research Council (GB) | 2018-02-14 | — | — | EP | claimed |
| WO-2016162689-A1 | INHIBITORS AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2016-10-13 | — | — | WO | claimed |
| CN-107820518-B | Methods for selecting phosphatase selective inhibitors and non-selective phosphatase inhibitors | 英国研究与创新署 | 2023-04-21 | — | — | CN | disclosed |
| US-20220313628-A1 | METHODS FOR SELECTING PHOSPHATASE SELECTIVE AND NON-SELECTIVE PHOSPHATASE INHIBITORS | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2022-10-06 | — | — | US | disclosed |
| US-11364211-B2 | Methods for selecting phosphatase selective and non-selective phosphatase inhibitors | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2022-06-21 | — | — | US | disclosed |
| US-11364211-B2 | Methods for selecting phosphatase selective and non-selective phosphatase inhibitors | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2022-06-21 | — | — | US | disclosed |
| US-11337941-B2 | Inhibitors and their uses | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2022-05-24 | — | — | US | disclosed |
| US-11337941-B2 | Inhibitors and their uses | UNITED KINGDOM RESEARCH AND INNOVATION (GB) | 2022-05-24 | — | — | US | disclosed |
| US-20180111896-A1 | INHIBITORS AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2018-04-26 | — | — | US | disclosed |
| EP-3280404-A1 | METHODS FOR SELECTING PHOSPHATASE SELECTIVE AND NON-SELECTIVE PHOSPHATASE INHIBITORS | Medical Research Council (GB) | 2018-02-14 | — | — | EP | disclosed |
| EP-3280405-A1 | INHIBITORS AND THEIR USES | Medical Research Council (GB) | 2018-02-14 | — | — | EP | disclosed |
| WO-2016162688-A1 | METHODS FOR SELECTING PHOSPHATASE SELECTIVE AND NON-SELECTIVE PHOSPHATASE INHIBITORS | MEDICAL RESEARCH COUNCIL (GB) | 2016-10-13 | — | — | WO | disclosed |
| WO-2016162689-A1 | INHIBITORS AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2016-10-13 | — | — | WO | disclosed |
| WO-2016162689-A1 | INHIBITORS AND THEIR USES | MEDICAL RESEARCH COUNCIL (GB) | 2016-10-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180125801-A1 | METHODS FOR SELECTING PHOSPHATASE SELECTIVE AND NON-SELECTIVE PHOSPHATASE INHIBITORS | PTPA, DUSP15, PPA1 | POLB 3576/4885HTT 3653/4885KDM4E 532/4885 |
| US-20180111896-A1 | INHIBITORS AND THEIR USES | PPP1R1B, PPP5C, PPP1R15A | POLB 3558/4885HTT 117/4885KDM4E 1965/4885 |
| US-11364211-B2 | Methods for selecting phosphatase selective and non-selective phosphatase inhibitors | PTPA, DUSP15, PPA1 | POLB 3576/4885HTT 3653/4885KDM4E 532/4885 |
| US-20220313628-A1 | METHODS FOR SELECTING PHOSPHATASE SELECTIVE AND NON-SELECTIVE PHOSPHATASE INHIBITORS | PTPA, DUSP15, DUSP1 | POLB 3627/4885HTT 3678/4885KDM4E 493/4885 |
| US-20200297668-A1 | INHIBITORS AND THEIR USES | PPP1R1B, PPP5C, PPP1R15A | POLB 3558/4885HTT 117/4885KDM4E 1965/4885 |
| US-11337941-B2 | Inhibitors and their uses | PPP1R1B, PPP5C, PPP1R15A | POLB 3558/4885HTT 117/4885KDM4E 1965/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.