Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | BCHE | P06276 | 1/20 | 0.54 |
| ▸ | ACHE | P22303 | 1/20 | 0.54 |
| ▸ | GRM5 | P41594 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL811061 | 0.94 | ALDH1A1 (0.76) | ALDH1A1CYP3A4MAPK1GAAMEN1 | |
| SCHEMBL14458252 | 0.89 | HTT (0.65) | ALDH1A1CYP3A4MAPK1GAAMEN1 | |
| SCHEMBL11590997 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL5524377 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL4401275 | 0.89 | GAA (0.84) | ALDH1A1CYP3A4GAAMEN1KMT2A | |
| SCHEMBL1024710 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL5028733 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL19651363 | 0.89 | GAA (0.84) | ALDH1A1CYP3A4GAAMEN1KMT2A | |
| SCHEMBL19651364 | 0.89 | GAA (0.84) | ALDH1A1CYP3A4GAAMEN1KMT2A | |
| SCHEMBL11589601 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2699542-B1 | PROCESS FOR THE MANUFACTURE OF DIHALODIPHENYLSULFONES | SOLVAY SPECIALTY POLYMERS USA (US) | 2016-10-12 | — | — | EP | disclosed |