Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 2/20 | 0.46 |
| ▸ | GRM5 | P41594 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2696615 | 0.95 | HTT (0.71) | HTTSMN1; SMN2L3MBTL1TDP1NPSR1 | |
| SCHEMBL14458257 | 0.95 | HTT (0.71) | HTTSMN1; SMN2L3MBTL1TDP1NPSR1 | |
| SCHEMBL17247214 | 0.91 | HTT (0.76) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL16621782 | 0.91 | HTT (0.76) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL822844 | 0.91 | HTT (0.76) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL23957972 | 0.91 | HTT (0.76) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL12769542 | 0.91 | HTT (0.76) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL822642 | 0.91 | ALDH1A1 (0.64) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 | |
| SCHEMBL18133333 | 0.89 | ALDH1A1 (0.67) | HTTSMN1; SMN2ALDH1A1CYP3A4MAPK1 | |
| SCHEMBL10084171 | 0.86 | HTT (0.85) | HTTSMN1; SMN2L3MBTL1TDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7244778-B2 | Filler reinforced polyether imide resin composition and molded article thereof | GENERAL ELECTRIC COMPANY (US) | 2007-07-17 | — | — | US | disclosed |