Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.38 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CHIT1 | Q13231 | 7/20 | 0.36 |
| ▸ | CHIA | Q9BZP6 | 6/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825799 | 0.84 | KMT2A (0.45) | ADORA3ADORA2AADORA1CRHBPCRHR2 | |
| SCHEMBL16825745 | 0.84 | KMT2A (0.45) | ADORA3ADORA2AADORA1CRHBPCRHR2 | |
| SCHEMBL16825741 | 0.84 | KMT2A (0.45) | ADORA3ADORA2AADORA1CRHBPCRHR2 | |
| SCHEMBL16825978 | 0.78 | SIGMAR1 (0.52) | KCNH2KMT2ASIGMAR1 | |
| SCHEMBL16825915 | 0.78 | SIGMAR1 (0.52) | KCNH2KMT2ASIGMAR1 | |
| SCHEMBL16825916 | 0.78 | SIGMAR1 (0.52) | KCNH2KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL18129142 | 0.78 | SIGMAR1 (0.54) | KCNH2KMT2ASIGMAR1 | |
| Hydrochloric Acid SCHEMBL18129143 | 0.78 | SIGMAR1 (0.54) | KCNH2KMT2ASIGMAR1 | |
| SCHEMBL16826074 | 0.76 | TSHR (0.48) | MCHR1KMT2A | |
| SCHEMBL16825644 | 0.74 | ALDH1A1 (0.54) | ADORA2ACRHBPCRHR2ALDH1A1CHIA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INSTITUTE FOR DRUG DISCOVERY, LLC | 2016-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160297823-A1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | CMA1, CHIA, AADAC | ADORA3 172/4885ADORA2A 1794/4885ADORA1 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.