Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 19/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17087030 | 0.87 | GLS (0.66) | GLS | |
| SCHEMBL16379545 | 0.86 | GLS (0.73) | GLS | |
| SCHEMBL18122527 | 0.85 | GLS (0.77) | GLS | |
| SCHEMBL16379547 | 0.85 | GLS (0.68) | GLS | |
| SCHEMBL15782614 | 0.85 | GLS (0.77) | GLS | |
| SCHEMBL17087062 | 0.85 | GLS (0.77) | GLS | |
| SCHEMBL18137309 | 0.85 | GLS (0.68) | GLS | |
| SCHEMBL17087032 | 0.84 | GLS (0.66) | GLS | |
| SCHEMBL15782842 | 0.84 | GLS (0.67) | GLS | |
| SCHEMBL16384713 | 0.83 | GLS (0.78) | GLS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016164401-A1 | TREATMENT OF LUNG CANCER WITH INHIBITORS OF GLUTAMINASE | CALITHERA BIOSCIENCES, INC. (US) | 2016-10-13 | — | — | WO | disclosed |