SCHEMBL181372

SCHEMBL181372

Cc1ccc(N=C=S)cc1N=C=O

nearest known ligand 0.79

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 6/20 0.79
TRPA1 O75762 1/20 0.79
ALDH1A1 P00352 4/20 0.43
LMNA P02545 1/20 0.43
TDP1 Q9NUW8 4/20 0.39
MAPK1 P28482 1/20 0.39
KDM4E B2RXH2 3/20 0.37
USP2 O75604 3/20 0.37
MAPT P10636 3/20 0.37
HPGD P15428 3/20 0.37
HSD17B10 Q99714 3/20 0.37
RAD51 Q06609 3/20 0.37
P2RY6 Q15077 2/20 0.37
LTA P01374 2/20 0.37
P2RX3 P56373 2/20 0.37
RAD1 O60671 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
MEN1 O00255 1/20 0.37
NPC1 O15118 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29454984 1.00 CYP3A4 (0.79) CYP3A4TRPA1ALDH1A1LMNATDP1
SCHEMBL6907530 0.93 CYP3A4 (0.79) CYP3A4TRPA1ALDH1A1LMNATDP1
Toluene Diisocyanate SCHEMBL28174227 0.89 CYP3A4 (1.00) CYP3A4TRPA1ALDH1A1LMNATDP1
Toluene Diisocyanate SCHEMBL29350148 0.89 CYP3A4 (1.00) CYP3A4TRPA1ALDH1A1LMNATDP1
Toluene Diisocyanate SCHEMBL19733056 0.89 CYP3A4 (1.00) CYP3A4TRPA1ALDH1A1LMNATDP1
SCHEMBL484205 0.89 CYP3A4 (0.60) CYP3A4TRPA1ALDH1A1LMNATDP1
Toluene Diisocyanate SCHEMBL29737260 0.89 CYP3A4 (1.00) CYP3A4TRPA1ALDH1A1LMNATDP1
SCHEMBL29463953 0.89 CYP3A4 (0.60) CYP3A4TRPA1ALDH1A1LMNATDP1
Toluene Diisocyanate SCHEMBL15384 0.89 CYP3A4 (1.00) CYP3A4TRPA1ALDH1A1LMNATDP1
Toluene Diisocyanate SCHEMBL6219230 0.87 CYP3A4 (0.96) CYP3A4TRPA1ALDH1A1LMNATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 709 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0216272-B1 IMMOBILIZATION OF BIOCATALYSTS ON GRANULAR DIATOMACEOUS EARTH HAARMANN & REIMER CORP. (US) 1993-05-26 EP claimed
EP-0234415-B1 METHOD FOR THE PREPARATION OF AN ENZYME-CONTAINING CELL IMMOBILIZED CONJUGATE AND THE IMMOBILIZED CONJUGATE PRODUCED THEREBY HAARMANN & REIMER CORP. (US) 1991-07-10 EP claimed
US-4757008-A Enzyme immobilization in a macroporous non-ionic resin MILES INC. (US) 1988-07-12 US claimed
US-4713333-A Immobilization of biocatalysts on granular diatomaceous earth MILES LABORATORIES, INC. (US) 1987-12-15 US claimed
EP-0234415-A2 Method for the preparation of an enzyme-containing cell immobilized conjugate and the immobilized conjugate produced thereby HAARMANN & REIMER CORP. (US) 1987-09-02 EP claimed
EP-0230649-A1 Immobilization of phenylaline ammonia-lyase MILES INC. (US) 1987-08-05 EP claimed
EP-0216272-A2 Immobilization of biocatalysts on granular diatomaceous earth HAARMANN & REIMER CORP. (US) 1987-04-01 EP claimed
EP-0104571-A2 Immobilization of biocatalysts on granular carbon MILES INC. (US) 1984-04-04 EP claimed
US-4438196-A POLYAMINES MILES LABORATORIES, INC. (US) 1984-03-20 US claimed
US-3950222-A DIISOCYANATES AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JA) 1976-04-13 US claimed
US-20260146189-A1 ADHESIVE COMPOSITION, THE PREPARATION METHOD AND USE THEREOF COVESTRO DEUTSCHLAND AG (DE) 2026-05-28 US disclosed
EP-4748866-A1 AQUEOUS POLYURETHANE DISPERSIONS AND APPLICATIONS THEREOF Covestro Deutschland AG (DE) 2026-05-27 EP disclosed
EP-3983466-B1 AQUEOUS POLYURETHANE DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2026-02-18 EP disclosed
US-20250352663-A1 Nanoclusters Functionalized with Adenosine Triphosphate or an Analogue and Their Use UNIV LELAND STANFORD JUNIOR (US) 2025-11-20 US disclosed
EP-4396248-B1 AQUEOUS POLYURETHANE-UREA DISPERSION COVESTRO DEUTSCHLAND AG (DE) 2025-08-06 EP disclosed
US-4053590-A BLOOD SUBSTITUTE, PLASMA EXPANDER ALZA CORPORATION (US) 1977-10-11 US disclosed
US-4041208-A ENERGY ABSORBERS, LAMINATED GLASS SHEETS USEFUL AS AUTOMOBILE WINDSHIELDS PPG INDUSTRIES, INC. (US) 1977-08-09 US disclosed
US-4001200-A BLOOD SUBSTITUTE FOR CARRYING OXYGEN ALZA CORPORATION (US) 1977-01-04 US disclosed
US-4001401-A BLOOD SUBSTITUTE AND BLOOD PLASMA EXPANDER COMPRISING POLYHEMOGLOBIN ALZA CORPORATION (US) 1977-01-04 US disclosed
US-3950222-A DIISOCYANATES AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JA) 1976-04-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260146189-A1 ADHESIVE COMPOSITION, THE PREPARATION METHOD AND USE THEREOF PUF60, XRCC6, F7 CYP3A4 3864/4885TRPA1 2530/4885ALDH1A1 780/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.