SCHEMBL484205

SCHEMBL484205

Cc1ccc(N=C=S)cc1N=C=S

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.60
TRPA1 O75762 1/20 0.60
ALDH1A1 P00352 5/20 0.47
LMNA P02545 1/20 0.47
P2RY6 Q15077 2/20 0.42
MIF P14174 1/20 0.41
KDM4E B2RXH2 3/20 0.41
USP2 O75604 3/20 0.41
MAPT P10636 3/20 0.41
MEN1 O00255 1/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
BLM P54132 1/20 0.41
KMT2A Q03164 1/20 0.41
PNMT P11086 1/20 0.39
TDP1 Q9NUW8 4/20 0.38
HSD17B10 Q99714 4/20 0.38
HPGD P15428 3/20 0.38
LTA P01374 2/20 0.38
P2RX3 P56373 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29463953 1.00 CYP3A4 (0.60) CYP3A4TRPA1ALDH1A1LMNAP2RY6
SCHEMBL29454984 0.89 CYP3A4 (0.79) CYP3A4TRPA1ALDH1A1LMNAP2RY6
SCHEMBL181372 0.89 CYP3A4 (0.79) CYP3A4TRPA1ALDH1A1LMNAP2RY6
SCHEMBL6907530 0.89 CYP3A4 (0.79) CYP3A4TRPA1ALDH1A1LMNAP2RY6
SCHEMBL16707534 0.83 P2RY6 (0.42) CYP3A4TRPA1ALDH1A1LMNAP2RY6
SCHEMBL3036837 0.83 P2RY6 (0.45) CYP3A4TRPA1ALDH1A1LMNAP2RY6
SCHEMBL30785389 0.81 ALDH1A1 (0.49) CYP3A4TRPA1ALDH1A1LMNAMIF
SCHEMBL191588 0.81 ALDH1A1 (0.49) CYP3A4TRPA1ALDH1A1LMNAMIF
SCHEMBL4739068 0.80 P2RY6 (0.46) CYP3A4TRPA1ALDH1A1P2RY6MIF
SCHEMBL1020719 0.78 ALDH1A1 (0.46) CYP3A4TRPA1ALDH1A1LMNAMIF

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 606 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114411187-A Nitrogen-sulfur-doped porous carbon electrode material and preparation method and application thereof 万华化学集团股份有限公司 2022-04-29 CN claimed
US-20180133663-A1 HIGH SELECTIVITY CHEMICALLY CROSS-LINKED RUBBERY MEMBRANES AND THEIR USE FOR SEPARATIONS UOP LLC 2018-05-17 US claimed
US-8816003-B2 High plasticization-resistant cross-linked polymeric membranes for separations UOP LLC (US) 2014-08-26 US claimed
WO-2010008660-A1 HIGH PLASTICIZATION-RESISTANT CROSS-LINKED POLYMERIC MEMBRANES FOR SEPARATIONS UOP LLC (US) 2010-01-21 WO claimed
US-20090318620-A1 High Plasticization-Resistant Cross-Linked Polymeric Membranes for Separations UOP LLC 2009-12-24 US claimed
US-7616374-B2 Electrophoretic displays with improved high temperature performance SIPIX IMAGING, INC. (US) 2009-11-10 US claimed
US-20070035497-A1 Electrophoretic displays with improved high temperature performance E INK CALIFORNIA, LLC 2007-02-15 US claimed
US-20050256279-A1 Sulfur-containing composition for golf equipment, and method of using same JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT 2005-11-17 US claimed
US-20040120024-A1 Electrophoretic displays with improved high temperature performance SIPIX IMAGING, INC. 2004-06-24 US claimed
WO-2004027507-A1 ELECTROPHORETIC DISPLAYS WITH IMPROVED HIGH TEMPERATURE PERFORMANCE SIPIX IMAGING, INC. (US) 2004-04-01 WO claimed
US-4713333-A Immobilization of biocatalysts on granular diatomaceous earth MILES LABORATORIES, INC. (US) 1987-12-15 US claimed
EP-0234415-A2 Method for the preparation of an enzyme-containing cell immobilized conjugate and the immobilized conjugate produced thereby HAARMANN & REIMER CORP. (US) 1987-09-02 EP claimed
EP-0230649-A1 Immobilization of phenylaline ammonia-lyase MILES INC. (US) 1987-08-05 EP claimed
EP-0216272-A2 Immobilization of biocatalysts on granular diatomaceous earth HAARMANN & REIMER CORP. (US) 1987-04-01 EP claimed
EP-0098814-B1 ANTITHROMBIN-HEPARIN COMPLEX KabiVitrum AB (SE) 1986-10-15 EP claimed
EP-0104571-A2 Immobilization of biocatalysts on granular carbon MILES INC. (US) 1984-04-04 EP claimed
US-4438196-A POLYAMINES MILES LABORATORIES, INC. (US) 1984-03-20 US claimed
EP-0098814-A1 Antithrombin-heparin complex KabiVitrum AB (SE) 1984-01-18 EP claimed
US-4154913-A ADDITION POLYMER ENDCAPPED WITH POLYISOCYANATE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1979-05-15 US claimed
US-4070344-A WITH POLYISOCYANATE, AMIDE, HYDROLYSIS THE FIRESTONE TIRE AND RUBBER COMPANY (US) 1978-01-24 US claimed