Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR5A | P47898 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.32 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838459 | 0.82 | PBRM1 (0.39) | HTR2CHTR2AHTR2BMAPTALDH1A1 | |
| SCHEMBL1153007 | 0.81 | MAP3K14 (0.35) | HTR2CPDE3BPDE3AHTR1AHTR1D | |
| SCHEMBL6989515 | 0.74 | ACHE (0.41) | MAPK1KMT2AGAAACHETSHR | |
| SCHEMBL1814326 | 0.74 | NPC1 (0.35) | HTR2CPDE3BPDE3AHTR1AHTR1D | |
| SCHEMBL15839587 | 0.73 | KMT2A (0.34) | HTR2CPDE3BPDE3AMAPK1KMT2A | |
| SCHEMBL1812688 | 0.72 | PDE7A (0.44) | MAPK1KMT2AMAPTALDH1A1MEN1 | |
| SCHEMBL4433341 | 0.70 | GAA (0.40) | KMT2AGAACRHBPCRHR2HPGD | |
| SCHEMBL1813846 | 0.69 | ACHE (0.31) | HTR2CHTR1AHTR1DHTR7HTR5A | |
| SCHEMBL14405342 | 0.69 | KMT2A (0.36) | HTR2CHTR5AMAPK1KMT2AGAA | |
| SCHEMBL5929398 | 0.69 | GAA (0.32) | HTR2CGAAHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-09-01 | — | — | US | disclosed |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-08-11 | — | — | US | disclosed |
| US-7947704-B2 | 2,4,6-phenyl-substituted cyclic ketoenols | BAYER CROPSCIENCE AG (DE) | 2011-05-24 | — | — | US | disclosed |
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | BAYER CROPSCIENCE AG (DE) | 2007-12-27 | — | — | US | disclosed |
| EP-1732930-A2 | 2,4,6-PHENYLSUBSTITUTED CYCLIC KETOENOLES | Bayer CropScience Aktiengesellschaft (DE) | 2006-12-20 | — | — | EP | disclosed |
| WO-2005092897-A2 | 2,4,6-PHENYLSUBSTITUTED CYCLIC KETOENOLES | BAYER CROPSCIENCE AG (DE) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070298968-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | CYP4X1, KCNE1, KDM4E | HTR2C 2657/4885PDE3B 1183/4885PDE3A 1295/4885 |
| US-20110195842-A1 | 2,4,6-Phenyl-Substituted Cyclic Ketoenols | CYP4X1, KCNE1, KDM4E | HTR2C 2657/4885PDE3B 1183/4885PDE3A 1295/4885 |
| US-20110213160-A1 | 2,4,6-Phenyl-Substituted Derivatives | CYP4X1, KDM4E, KCNE1 | HTR2C 2436/4885PDE3B 1426/4885PDE3A 1641/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.