Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Xanthone. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 8/20 | 0.75 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.75 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | GLA | P06280 | 1/20 | 0.75 |
| ▸ | MAPT | P10636 | 1/20 | 0.75 |
| ▸ | HPGD | P15428 | 1/20 | 0.75 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.75 |
| ▸ | CASP1 | P29466 | 1/20 | 0.75 |
| ▸ | CASP7 | P55210 | 1/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.75 |
| ▸ | NPC1 | O15118 | 4/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | TTR | P02766 | 3/20 | 0.64 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthone SCHEMBL27726954 | 0.94 | MAOA (0.78) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Xanthone SCHEMBL11245548 | 0.89 | MAOA (0.86) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Xanthone SCHEMBL28434710 | 0.89 | MAOA (0.95) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Xanthone SCHEMBL9738572 | 0.89 | NPC1 (0.73) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Xanthone SCHEMBL29358061 | 0.87 | MAOA (1.00) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Xanthone SCHEMBL41161 | 0.87 | MAOA (1.00) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Xanthone SCHEMBL29398266 | 0.87 | MAOA (1.00) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Acetic Acid SCHEMBL7328686 | 0.87 | MAOA (0.84) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Xanthone SCHEMBL2354794 | 0.87 | MAOA (1.00) | MAOAKDM4ECYP3A4ALDH1A1GLA | |
| Xanthone SCHEMBL31175941 | 0.86 | MAOA (0.67) | MAOAKDM4ECYP3A4ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2026105817-A1 | ADHESIVE FILM AND WOUND BODY | 積水化学工業株式会社 | 2026-05-21 | — | — | WO | disclosed |
| WO-2025058045-A1 | ADHESIVE FILM, METHOD FOR PRODUCING ADHESIVE FILM, ADHESIVE RESIN COMPOSITION, AND METHOD FOR PRODUCING SEMICONDUCTOR DEVICE | 積水化学工業株式会社 | 2025-03-20 | — | — | WO | disclosed |
| WO-2024154729-A1 | ADHESIVE FILM, TEMPORARY FIXING MATERIAL, CURED PRODUCT, LAMINATE, AND METHOD OF PRODUCING ELECTRONIC COMPONENT | 積水化学工業株式会社 | 2024-07-25 | — | — | WO | disclosed |
| CN-117946519-A | Curable resin composition, temporary fixing material, and method for producing electronic component | 积水化学工业株式会社 | 2024-04-30 | — | — | CN | disclosed |
| CN-117946520-A | Curable resin composition, temporary fixing material, and method for producing electronic component | 积水化学工业株式会社 | 2024-04-30 | — | — | CN | disclosed |
| CN-115702212-B | Curable resin composition, temporary fixing material, and method for producing electronic component | 积水化学工业株式会社 | 2024-01-12 | — | — | CN | disclosed |
| US-20230348767-A1 | PROVISIONAL FIXATION MATERIAL AND METHOD FOR PRODUCING ELECTRONIC COMPONENT | SEKISUI CHEMICAL CO., LTD. (JP) | 2023-11-02 | — | — | US | disclosed |
| US-20230312923-A1 | CURABLE RESIN COMPOSITION, TEMPORARY FIXING MATERIAL, AND ELECTRONIC COMPONENT MANUFACTURING METHOD | SEKISUI CHEMICAL CO., LTD. (JP) | 2023-10-05 | — | — | US | disclosed |
| CN-115917706-A | Temporary fixing material and method for manufacturing electronic component | 积水化学工业株式会社 | 2023-04-04 | — | — | CN | disclosed |
| CN-115702212-A | Curable resin composition, temporary fixing material, and method for producing electronic component | 积水化学工业株式会社 | 2023-02-14 | — | — | CN | disclosed |
| CN-102711809-B | Use anti-endoglin antibody and anti-VEGF agent therapeutic alliance cancer | TRACON PHARMACEUTICALS, INC. (US) | 2015-09-30 | — | — | CN | disclosed |
| CN-104788562-A | Endoglin antibodies | TRACON PHARMACEUTICALS INC | 2015-07-22 | — | — | CN | disclosed |
| CN-104684580-A | Antibody formulations and uses thereof | TRACON PHARMACEUTICALS INC | 2015-06-03 | — | — | CN | disclosed |
| CN-102762227-B | Endothelin antibodies | TRACON PHARMACEUTICALS INC | 2015-04-22 | — | — | CN | disclosed |
| CN-102939109-A | Conjugates of drugs and protein-binding prodrugs | KTB TUMORFORSCHUNGS GMBH | 2013-02-20 | — | — | CN | disclosed |
| CN-102762227-A | Endothelin antibodies | TRACON PHARMACEUTICALS INC | 2012-10-31 | — | — | CN | disclosed |
| CN-102753179-A | 1,4-benzodiazepine-2,5-diones and related compounds with therapeutic properties | UNIV MICHIGAN | 2012-10-24 | — | — | CN | disclosed |
| CN-102711809-A | Combination therapy of cancer with anti-endoglin antibodies and anti-VEGF agents | TRACON PHARMACEUTICALS INC | 2012-10-03 | — | — | CN | disclosed |
| CN-1344159-B | Combinations for treatment of diseases involving angiogenesis | ANGIOGENE PHARM LTD | 2011-09-28 | — | — | CN | disclosed |
| CN-1344159-A | Combinations for treatment of diseases involving angiogenesis | ANGIOGENE PHARM LTD (GB) | 2002-04-10 | — | — | CN | disclosed |