Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.73 |
| ▸ | RAB9A | P51151 | 2/20 | 0.73 |
| ▸ | MAOA | P21397 | 7/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | GLA | P06280 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | HPGD | P15428 | 1/20 | 0.64 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TTR | P02766 | 4/20 | 0.61 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Xanthone SCHEMBL18138444 | 0.89 | MAOA (0.75) | NPC1RAB9AMAOAALDH1A1MAPT | |
| Xanthone SCHEMBL27726954 | 0.87 | MAOA (0.78) | NPC1RAB9AMAOAALDH1A1MAPT | |
| Xanthone SCHEMBL9762833 | 0.85 | MAOA (0.69) | NPC1RAB9AMAOAALDH1A1MAPT | |
| Xanthone SCHEMBL28077164 | 0.85 | TTR (0.75) | NPC1RAB9AMAOAALDH1A1MAPT | |
| SCHEMBL10882826 | 0.85 | NPC1 (1.00) | NPC1RAB9AMAOAALDH1A1MAPT | |
| Xanthone SCHEMBL11245548 | 0.82 | MAOA (0.86) | NPC1RAB9AMAOAALDH1A1MAPT | |
| Xanthone SCHEMBL28434710 | 0.82 | MAOA (0.95) | NPC1RAB9AMAOAALDH1A1MAPT | |
| Xanthone SCHEMBL5842358 | 0.81 | MAOA (0.62) | NPC1RAB9AMAOAALDH1A1MAPT | |
| Xanthone SCHEMBL29358061 | 0.80 | MAOA (1.00) | NPC1RAB9AMAOAALDH1A1MAPT | |
| Xanthone SCHEMBL2354794 | 0.80 | MAOA (1.00) | NPC1RAB9AMAOAALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5085886-A | Dielectric polymer is formed on substrate from the ether reaction product of dicyclopentadiene and a phenol | ALLIED-SIGNAL INC. (US) | 1992-02-04 | — | — | US | disclosed |