SCHEMBL181393

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL182029	0.80	HDAC1 (0.53)	HDAC1HDAC2HDAC8HDAC6CTSB
	SCHEMBL7898196	0.80	HDAC3 (0.54)	HDAC1HDAC2HDAC8HDAC6HDAC3
	SCHEMBL9895471	0.80	HDAC3 (0.54)	HDAC1HDAC2HDAC8HDAC6HDAC3
	SCHEMBL9895603	0.79	HDAC3 (0.56)	HDAC1HDAC2HDAC8HDAC6HDAC3
	SCHEMBL7897997	0.79	HDAC3 (0.56)	HDAC1HDAC2HDAC8HDAC6HDAC3
	SCHEMBL28787337	0.78	HDAC1 (0.50)	HDAC1HDAC2HDAC8HDAC6TPSAB1
	SCHEMBL9895152	0.78	HDAC3 (0.54)	HDAC1HDAC2HDAC8HDAC6HDAC3
	SCHEMBL7896020	0.78	HDAC3 (0.54)	HDAC1HDAC2HDAC8HDAC6HDAC3
	SCHEMBL7897082	0.77	NR1H4 (0.43)	HDAC1HDAC8HDAC6TPSAB1TPSD1
	SCHEMBL181804	0.76	HDAC3 (0.55)	HDAC1HDAC2HDAC8HDAC6HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.