SCHEMBL182029

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL181393	0.80	HDAC1 (0.41)	HDAC1HDAC2HDAC8HDAC6CTSB
	SCHEMBL5320356	0.79	LTA4H (0.59)	LTA4H
	SCHEMBL5678125	0.77	LTA4H (0.57)	LTA4HCTSBCTSSKMT2A
	Hydrochloric Acid SCHEMBL6008696	0.77	LTA4H (0.57)	LTA4H
	SCHEMBL9894470	0.76	HDAC3 (0.57)	HDAC1HDAC2HDAC8HDAC6LTA4H
	SCHEMBL9894467	0.76	HDAC3 (0.57)	HDAC1HDAC2HDAC8HDAC6LTA4H
	SCHEMBL7896997	0.74	LTA4H (0.46)	HDAC1HDAC2HDAC8HDAC6LTA4H
	SCHEMBL1837653	0.72	CTSB (0.67)	HDAC1HDAC2HDAC8HDAC6CTSB
	SCHEMBL10458177	0.72	LTA4H (0.51)	LTA4HMEN1KMT2A
	SCHEMBL16112075	0.71	LTA4H (0.44)	LTA4HCTSBCTSSMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.