Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.41 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.41 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7889390 | 0.79 | HDAC1 (0.42) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL27652150 | 0.79 | HDAC3 (0.60) | HDAC1HDAC2HDAC3EPHX1ALDH1A1 | |
| SCHEMBL181393 | 0.78 | HDAC1 (0.41) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL27630590 | 0.77 | HDAC3 (0.62) | HDAC1HDAC2HDAC3EPHX1ALDH1A1 | |
| SCHEMBL19716961 | 0.77 | ITGB3 (0.43) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL1411017 | 0.77 | HDAC1 (0.40) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL19716963 | 0.77 | ITGB3 (0.43) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL1411260 | 0.77 | HDAC1 (0.39) | HDAC1HDAC2HDAC3HDAC8HDAC6 | |
| SCHEMBL27742584 | 0.76 | F2 (0.63) | HDAC1HDAC2HDAC3EPHX1ALDH1A1 | |
| SCHEMBL1410836 | 0.76 | ANPEP (0.42) | HDAC1HDAC2HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101959534-B | Enzyme and receptor modulation | CHROMA THERAPEUTICS LTD | 2013-11-27 | — | — | CN | disclosed |
| CN-101959534-A | Enzyme and receptor modulation | CHROMA THERAPEUTICS LTD | 2011-01-26 | — | — | CN | disclosed |