Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 3/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 4/20 | 0.31 |
| ▸ | CES1 | P23141 | 4/20 | 0.31 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998145 | 1.00 | TSHR (0.41) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL9007932 | 0.98 | TSHR (0.40) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL27546632 | 0.98 | — | — | |
| SCHEMBL10503405 | 0.90 | — | — | |
| SCHEMBL10503758 | 0.84 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10503829 | 0.84 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10505681 | 0.84 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10504172 | 0.84 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10503059 | 0.84 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10503325 | 0.84 | CES2 (0.47) | TSHRCES2GMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402356-A2 | Modified 2',3'-dideoxynucleosides for treatment infections caused by human immunodeficiency virus (HIV) multidrug resistant strains, method of their synthesis and the pharmaceutical agent containing these nucleosides | Instytut Biochemii I Biofizyki Pan (PL) | 2012-01-04 | — | — | EP | claimed |
| EP-2402356-A3 | Modified 2',3'-dideoxynucleosides for treatment infections caused by human immunodeficiency virus (HIV) multidrug resistant strains, method of their synthesis and the pharmaceutical agent containing these nucleosides | Instytut Biochemii I Biofizyki Pan (PL) | 2012-07-18 | — | — | EP | disclosed |
| EP-2402356-A2 | Modified 2',3'-dideoxynucleosides for treatment infections caused by human immunodeficiency virus (HIV) multidrug resistant strains, method of their synthesis and the pharmaceutical agent containing these nucleosides | Instytut Biochemii I Biofizyki Pan (PL) | 2012-01-04 | — | — | EP | disclosed |
| EP-2402356-A2 | Modified 2',3'-dideoxynucleosides for treatment infections caused by human immunodeficiency virus (HIV) multidrug resistant strains, method of their synthesis and the pharmaceutical agent containing these nucleosides | Instytut Biochemii I Biofizyki Pan (PL) | 2012-01-04 | — | — | EP | disclosed |