Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998145 | 0.98 | TSHR (0.41) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL181406 | 0.98 | TSHR (0.41) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL27546632 | 0.95 | — | — | |
| SCHEMBL10503405 | 0.88 | — | — | |
| SCHEMBL10504371 | 0.86 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10504018 | 0.86 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10503059 | 0.86 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10503829 | 0.86 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10503758 | 0.86 | CES2 (0.47) | TSHRCES2GMNNTP53POLB | |
| SCHEMBL10503325 | 0.86 | CES2 (0.47) | TSHRCES2GMNNTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571689-A | Method of N-acylating peptide and proteins with diheteroatom substituted analogs of myristic acid | WASHINGTON UNIVERSITY (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0441765-B1 | Novel fatty acid analog enzyme substrates | UNIV WASHINGTON (US) | 1994-05-11 | — | — | EP | disclosed |
| US-5082967-A | Myristolyation | WASHINGTON UNIVERSITY (US) | 1992-01-21 | — | — | US | disclosed |
| EP-0441765-A1 | Novel fatty acid analog enzyme substrates | WASHINGTON UNIVERSITY (US) | 1991-08-14 | — | — | EP | disclosed |