SCHEMBL18143023

SCHEMBL18143023

COCC1=CC(=NO)C=CC1=NO

nearest known ligand 0.32

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ PABPC1 P11940 1/20 0.32
▸ HSP90AA1 P07900 1/20 0.30
▸ GAA P10253 1/20 0.30
▸ PKM P14618 1/20 0.30
▸ MAPK1 P28482 1/20 0.30
▸ GFER P55789 1/20 0.30
▸ NPSR1 Q6W5P4 1/20 0.30
▸ TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9911035 1.00 PABPC1 (0.32) PABPC1HSP90AA1GAAPKMMAPK1
SCHEMBL9886534 1.00 PABPC1 (0.32) PABPC1HSP90AA1GAAPKMMAPK1
SCHEMBL9886538 1.00 PABPC1 (0.32) PABPC1HSP90AA1GAAPKMMAPK1
SCHEMBL9911034 1.00 PABPC1 (0.32) PABPC1HSP90AA1GAAPKMMAPK1
SCHEMBL22980335 0.81 ERBB2 (0.35) PKMMAPK1TDP1
SCHEMBL22980337 0.81 ERBB2 (0.35) PKMMAPK1TDP1
SCHEMBL9886530 0.80 ERBB2 (0.34) —
SCHEMBL9911033 0.80 ERBB2 (0.34) —
SCHEMBL9886539 0.80 — —
SCHEMBL9105522 0.80 ERBB2 (0.34) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4013739-B1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE WELLA GERMANY GMBH (DE) 2024-10-02 — — EP claimed
US-20220298101-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE WELLA GERMANY GMBH (DE) 2022-09-22 — — US claimed
CN-114787122-A Novel polycondensation synthesis of 2-methoxymethyl-p-phenylenediamine 威娜德国有限责任公司 2022-07-22 — — CN claimed
EP-4013739-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE Wella Germany GmbH (DE) 2022-06-22 — — EP claimed
WO-2021028506-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE COTY INC. (US) 2021-02-18 — — WO claimed
EP-2646408-B1 PROCESS FOR THE PREPARATION OF 2-METHOXYMETHYL-1,4-BENZENEDIAMINE, ITS DERIVATIVES THEREOF AND THE SALTS THEREOF PROCTER & GAMBLE (US) 2016-10-19 — — EP claimed
US-12122734-B2 Telescoping syntheses of 2-methoxymethyl-p-phenylenediamine WELLA GERMANY GMBH (DE) 2024-10-22 — — US disclosed
EP-4013739-B1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE WELLA GERMANY GMBH (DE) 2024-10-02 — — EP disclosed
US-20220298101-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE WELLA GERMANY GMBH (DE) 2022-09-22 — — US disclosed
CN-114787122-A Novel polycondensation synthesis of 2-methoxymethyl-p-phenylenediamine 威娜德国有限责任公司 2022-07-22 — — CN disclosed
EP-4013739-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE Wella Germany GmbH (DE) 2022-06-22 — — EP disclosed
WO-2021028506-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE COTY INC. (US) 2021-02-18 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12122734-B2 Telescoping syntheses of 2-methoxymethyl-p-phenylenediamine PNMT, TYR, DDT PABPC1 1241/4885HSP90AA1 4455/4885GAA 2819/4885
US-20220298101-A1 NEW TELESCOPING SYNTHESES OF 2-METHOXYMETHYL-P-PHENYLENEDIAMINE PNMT, TYR, DDT PABPC1 1604/4885HSP90AA1 4700/4885GAA 3216/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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