Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9662426 | 0.83 | TSHR (0.32) | TSHR | |
| SCHEMBL2289310 | 0.81 | — | — | |
| SCHEMBL15302786 | 0.81 | TSHR (0.32) | TSHR | |
| SCHEMBL17968222 | 0.81 | — | — | |
| SCHEMBL4518490 | 0.77 | — | — | |
| SCHEMBL4632783 | 0.77 | — | — | |
| SCHEMBL15301994 | 0.76 | TSHR (0.35) | TSHR | |
| SCHEMBL2288365 | 0.76 | TSHR (0.35) | TSHR | |
| SCHEMBL2292470 | 0.74 | TSHR (0.33) | TSHR | |
| SCHEMBL15302165 | 0.73 | TSHR (0.40) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 557 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3838901-B1 | COMPOUND FOR TREATMENT OF RABIES AND METHOD FOR TREATMENT OF RABIES | IRIMAJIRI THERAPEUTICS INC (JP) | 2023-09-27 | — | — | EP | claimed |
| EP-3296312-B1 | SYNTHESIS OF PROTECTED 3'-AMINO 5'-PHOSPHORAMIDITE NUCLEOSIDE MONOMERS | GERON CORP (US) | 2021-03-17 | — | — | EP | claimed |
| CN-108864172-B | Green synthesis method of 1, 2-di (trialkylsiloxy) cyclohexene | 上虞新和成生物化工有限公司 | 2020-09-29 | — | — | CN | claimed |
| EP-2970760-B1 | PHOTOCHROMIC ARTICLES THAT INCLUDE PHOTOCHROMIC-DICHROIC MATERIALS | TRANSITIONS OPTICAL INC (US) | 2019-06-26 | — | — | EP | claimed |
| EP-1778711-B1 | SYNTHESIS OF PROTECTED 3'-AMINO NUCLEOSIDE MONOMERS | GERON CORP (US) | 2017-08-16 | — | — | EP | claimed |
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-12 | — | — | US | claimed |
| US-20150315146-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYLETHYNYL)-BICYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-11-05 | — | — | US | claimed |
| US-20150305334-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYL ETHYNYL)-CYCLOHEXANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | BAYER CROPSCIENCE AG (DE) | 2015-10-29 | — | — | US | claimed |
| EP-2928297-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYLOALKENYL ETHYNYL)-BICYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-10-14 | — | — | EP | claimed |
| EP-2928296-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYLOALKENYL ETHYNYL)-CYCLOHEXANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | Bayer CropScience AG (DE) | 2015-10-14 | — | — | EP | claimed |
| US-5760276-A | TREATING SKIN DISORDERS, REDUCING SIDE EFFECTS OF RETINOIDS | ALLERGAN (US) | 1998-06-02 | — | — | US | claimed |
| US-5728846-A | RETENOIDS, RETINOID ACTIVITY; AGONISTS, ANTAGONISTS | ALLERGAN (US) | 1998-03-17 | — | — | US | claimed |
| EP-0321841-B1 | ESTER URETHANE (MET)ACRYLIC-ACID DERIVATIVES | BAYER AG (DE) | 1993-04-14 | — | — | EP | claimed |
| EP-0409273-A2 | Substituted isoxazole and isothiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1991-01-23 | — | — | EP | claimed |
| EP-0223735-B1 | PROCESS FOR THE PREPARATION OF HEMIAMINALES, HEMIAMINALES AND THEIR USE | CIBA-GEIGY AG (CH) | 1989-11-08 | — | — | EP | claimed |
| EP-0321841-A2 | Ester urethane (met)acrylic-acid derivatives | BAYER AG (DE) | 1989-06-28 | — | — | EP | claimed |
| EP-0286968-A2 | Substituted 1-arylpyrazoles | BAYER AG (DE) | 1988-10-19 | — | — | EP | claimed |
| US-4770968-A | INCORPORATED RELEASE AGENT | XEROX CORPORATION (US) | 1988-09-13 | — | — | US | claimed |
| US-4711943-A | IMPROVED OXYGEN PERMEABILITY AND STABILITY | SOLA U.S.A. INC. (US) | 1987-12-08 | — | — | US | claimed |
| US-4059576-A | CARDIOVASCULAR, OXYTOCICS | HOFFMANN-LA ROCHE, INC. (US) | 1977-11-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150322094-A1 | USE OF SUBSTITUTED 2,3-DIHYDRO-1-BENZOFURAN-4-CARBOXYLIC ACIDS OR SALTS THEREOF AS ACTIVE SUBSTANCES AGAINST ABIOTIC PLANT STRESS | CAT, HSF1, HPD | TSHR 4556/4885 |
| US-20150315146-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYLETHYNYL)-BICYCLOALKANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | AAK1, SYMPK, CBR1 | TSHR 4046/4885 |
| US-20150305334-A1 | USE OF SUBSTITUTED 1-(ARYL ETHYNYL)-, 1-(HETEROARYL ETHYNYL)-, 1-(HETEROCYCLYL ETHYNYL)- AND 1-(CYCLOALKENYL ETHYNYL)-CYCLOHEXANOLS AS ACTIVE AGENTS AGAINST ABIOTIC PLANT STRESS | CBR1, CAT, NAT1 | TSHR 3376/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.