Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.49 |
| ▸ | FEN1 | P39748 | 2/20 | 0.49 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.38 |
| ▸ | MMP1 | P03956 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.38 |
| ▸ | MMP7 | P09237 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | MMP13 | P45452 | 1/20 | 0.38 |
| ▸ | S100A4 | P26447 | 1/20 | 0.37 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.36 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29448266 | 1.00 | ALOX5AP (0.49) | ALOX5APFEN1DGAT1MMP1MMP2 | |
| SCHEMBL15341611 | 0.96 | FEN1 (0.54) | ALOX5APFEN1DGAT1MMP1MMP2 | |
| SCHEMBL15433177 | 0.89 | ALOX5AP (0.44) | ALOX5APFEN1MMP1MMP2MMP3 | |
| SCHEMBL14945929 | 0.83 | ALOX5AP (0.46) | ALOX5APFEN1DGAT1MMP1MMP2 | |
| SCHEMBL30665731 | 0.83 | ALOX5AP (0.45) | ALOX5APFEN1DGAT1MMP1MMP2 | |
| SCHEMBL12198995 | 0.83 | ALOX5AP (0.45) | ALOX5APFEN1DGAT1MMP1MMP2 | |
| SCHEMBL14520998 | 0.81 | DGAT1 (0.46) | ALOX5APFEN1DGAT1MMP1MMP2 | |
| SCHEMBL31310573 | 0.81 | DGAT1 (0.46) | ALOX5APFEN1DGAT1MMP1MMP2 | |
| SCHEMBL9179259 | 0.81 | FEN1 (0.55) | ALOX5APFEN1DGAT1MMP1MMP2 | |
| SCHEMBL22440624 | 0.80 | ALOX5AP (0.44) | ALOX5APFEN1DGAT1MMP1MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116948656-B | Application of ionic liquid in preparation of fluoroalkyl cyclohexyl biphenyl liquid crystal compounds | 河北美星化工有限公司 | 2024-07-09 | — | — | CN | disclosed |
| EP-4015598-B1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2024-05-22 | — | — | EP | disclosed |
| CN-116948656-A | Application of ionic liquid in preparation of fluoroalkyl cyclohexyl biphenyl liquid crystal compounds | 河北美星化工有限公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-3712230-B1 | LIQUID CRYSTAL COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-05-17 | — | — | EP | disclosed |
| EP-3712230-B1 | LIQUID CRYSTAL COMPOUNDS | MERCK PATENT GMBH (DE) | 2023-05-17 | — | — | EP | disclosed |
| US-11447701-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | MERCK PATENT GMBH (DE) | 2022-09-20 | — | — | US | disclosed |
| EP-4015598-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | Merck Patent GmbH (DE) | 2022-06-22 | — | — | EP | disclosed |
| EP-4015598-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | Merck Patent GmbH (DE) | 2022-06-22 | — | — | EP | disclosed |
| US-11208595-B2 | Liquid-crystalline compounds | MERCK PATENT GMBH (DE) | 2021-12-28 | — | — | US | disclosed |
| US-20210207029-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | MERCK PATENT GMBH (DE) | 2021-07-08 | — | — | US | disclosed |
| US-7951432-B2 | Five-ring liquid crystal compound having cyclohexane ring, liquid crystal composition, and liquid crystal display device | CHISSO CORPORATION (JP) | 2011-05-31 | — | — | US | disclosed |
| EP-2284148-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT | Chisso Corporation (JP) | 2011-02-16 | — | — | EP | disclosed |
| US-20090302273-A1 | FIVE-RING LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090302273-A1 | FIVE-RING LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2009-12-10 | — | — | US | disclosed |
| US-20090302273-A1 | FIVE-RING LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2009-12-10 | — | — | US | disclosed |
| US-7361388-B2 | Liquid-crystalline compounds having a tetrahydropyran ring | MERCK PATENT GMBH (DE) | 2008-04-22 | — | — | US | disclosed |
| US-20060289829-A1 | Liquid-crystalline compounds having a tetrahydropyran ring | MERCK PATENT GMBH (DE) | 2006-12-28 | — | — | US | disclosed |
| WO-2004106460-A1 | LIQUID-CRYSTALLINE COMPOUNDS HAVING A TETRAHYDROPYRAN RING | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |
| US-20020047103-A1 | Liquid crystalline compounds having a silane diyl group, liquid crystal compositions comprising the same and liquid crystal display devices | CHISSO PETROCHEMICAL CORPORATION (JP) | 2002-04-25 | — | — | US | disclosed |
| EP-1160251-A2 | Liquid crystalline compounds having a silane diyl group, liquid crystal compositions comprising the same and liquid crystal display devices | CHISSO CORPORATION (JP) | 2001-12-05 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11208595-B2 | Liquid-crystalline compounds | CHRM1, C1S, CHRM2 | ALOX5AP 3608/4885FEN1 3955/4885DGAT1 3864/4885 |
| US-11447701-B2 | Liquid-crystalline medium and liquid-crystal display comprising the same and compounds | NEFM, FES, SBDS | ALOX5AP 4632/4885FEN1 3092/4885DGAT1 4565/4885 |
| US-20090302273-A1 | FIVE-RING LIQUID CRYSTAL COMPOUND HAVING CYCLOHEXANE RING, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | ZYX, PYM1, CPNE4 | ALOX5AP 306/4885FEN1 3316/4885DGAT1 3729/4885 |
| US-20210207029-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME AND COMPOUNDS | NEFM, FES, SBDS | ALOX5AP 4632/4885FEN1 3092/4885DGAT1 4565/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.