SCHEMBL18151976

SCHEMBL18151976

c1cc(-c2cncc(-c3cccc(-c4cccc(-n5c6ccccc6c6ccccc65)c4)c3)c2)cc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 2/20 0.50
ATM Q13315 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPT P10636 3/20 0.38
GABRG2 P18507 1/20 0.37
GABRB3 P28472 1/20 0.37
GABRA5 P31644 1/20 0.37
GABRA3 P34903 1/20 0.37
CHRNB4 P30926 1/20 0.37
CHRNA3 P32297 1/20 0.37
CYP11B2 P19099 4/20 0.36
KMT2A Q03164 3/20 0.36
CYP11B1 P15538 2/20 0.36
IL1R1 P14778 1/20 0.36
MKNK1 Q9BUB5 1/20 0.35
MKNK2 Q9HBH9 1/20 0.35
MEN1 O00255 2/20 0.35
ALDH1A1 P00352 2/20 0.35
HTT P42858 2/20 0.35
DUSP3 P51452 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362914 1.00 L3MBTL1 (0.50) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL8400383 1.00 L3MBTL1 (0.50) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL612234 1.00 L3MBTL1 (0.50) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL29358123 1.00 L3MBTL1 (0.50) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL21453879 0.97 L3MBTL1 (0.47) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL21028244 0.97 ATM (0.52) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL28436068 0.97 ATM (0.47) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL29511975 0.95 L3MBTL1 (0.48) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL10024691 0.95 L3MBTL1 (0.48) L3MBTL1ATMKDM4EMAPTGABRG2
SCHEMBL17952933 0.94 L3MBTL1 (0.44) L3MBTL1ATMKDM4EMAPTGABRG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10305044-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-05-28 US disclosed
US-10305044-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2019-05-28 US disclosed
US-20160308139-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-20 US disclosed
US-20160308139-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-20 US disclosed
US-20160308139-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10305044-B2 Heterocyclic compound, light-emitting element, light-emitting device, electronic device, and lighting device CRY1, CYP1A1, NR2E3 L3MBTL1 522/4885ATM 4087/4885KDM4E 2956/4885
US-20160308139-A1 Heterocyclic Compound, Light-Emitting Element, Light-Emitting Device, Electronic Device, and Lighting Device CRY1, CYP1A1, NR2E3 L3MBTL1 522/4885ATM 4087/4885KDM4E 2956/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.