Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 11/20 | 0.79 |
| ▸ | CTNNB1 | P35222 | 11/20 | 0.79 |
| ▸ | MET | P08581 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 2/20 | 0.45 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.43 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152388 | 0.94 | CTNNB1 (0.81) | BCL9CTNNB1 | |
| SCHEMBL18152471 | 0.94 | BCL9 (0.82) | BCL9CTNNB1 | |
| SCHEMBL18152322 | 0.92 | BCL9 (0.82) | BCL9CTNNB1MET | |
| SCHEMBL18152394 | 0.91 | BCL9 (0.82) | BCL9CTNNB1METMCHR1 | |
| SCHEMBL18152447 | 0.91 | BCL9 (0.81) | BCL9CTNNB1METMEN1KMT2A | |
| SCHEMBL18165096 | 0.89 | BCL9 (0.98) | BCL9CTNNB1METMEN1KMT2A | |
| SCHEMBL20021897 | 0.85 | BCL9 (0.89) | BCL9CTNNB1METMEN1KMT2A | |
| SCHEMBL18165097 | 0.84 | CTNNB1 (0.98) | BCL9CTNNB1 | |
| SCHEMBL18165095 | 0.82 | BCL9 (0.98) | BCL9CTNNB1MET | |
| SCHEMBL20021886 | 0.82 | BCL9 (0.84) | BCL9CTNNB1METKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168524-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-10-20 | — | — | WO | disclosed |