Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.45 |
| ▸ | JAK2 | O60674 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | TGM2 | P21980 | 1/20 | 0.43 |
| ▸ | PARP1 | P09874 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | STS | P08842 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | YAP1 | P46937 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31663791 | 0.83 | PTPN2 (0.55) | PDE4BGPR119PARP1PARP2PIK3CD | |
| SCHEMBL18165189 | 0.82 | PDE4B (0.46) | USP30PDE4BJAK2JAK1GPR119 | |
| SCHEMBL6192978 | 0.80 | GPR119 (0.51) | GPR119TGM2STSNPC1ALDH1A1 | |
| Acetic Acid SCHEMBL6190067 | 0.79 | GPR119 (0.49) | GPR119TGM2STSNPC1ALDH1A1 | |
| SCHEMBL29619078 | 0.78 | NPC1 (0.52) | USP30PDE4BPIK3CDNPC1RAB9A | |
| SCHEMBL1927899 | 0.77 | USP30 (0.52) | USP30PDE4BJAK2JAK1GPR119 | |
| SCHEMBL4615967 | 0.77 | NAMPT (0.48) | GPR119STSNPC1ALDH1A1RAB9A | |
| SCHEMBL27092645 | 0.77 | MGLL (0.48) | PDE4BTGM2NPC1ALDH1A1TP53 | |
| SCHEMBL19404343 | 0.77 | TOP2A (0.51) | USP30PDE4BGPR119PIK3CDALDH1A1 | |
| SCHEMBL18165187 | 0.77 | TOP2A (0.51) | USP30PDE4BGPR119PIK3CDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016168524-A1 | SUBSTITUTED N-([1,1'-BIPHENYL]-3-YL)-[1,1'-BIPHENYL]-3-CARBOXAMIDE ANALOGS AS INHIBITORS FOR BETA-CATENIN/B-CELL LYMPHOMA 9 INTERACTIONS | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-10-20 | — | — | WO | disclosed |