Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152677 | 0.87 | CCNB2 (0.32) | — | |
| SCHEMBL18152659 | 0.81 | ADRB2 (0.33) | HTTADRB2 | |
| SCHEMBL18152712 | 0.77 | GRIN2D (0.38) | HTT | |
| SCHEMBL18152627 | 0.72 | CCNB2 (0.31) | — | |
| SCHEMBL18152638 | 0.67 | SMN1; SMN2 (0.41) | HTTADRB2 | |
| SCHEMBL4381077 | 0.63 | HTT (0.47) | HTT | |
| SCHEMBL13544184 | 0.60 | SMN1; SMN2 (0.50) | HTT | |
| SCHEMBL14722325 | 0.58 | HTT (0.68) | HTT | |
| SCHEMBL15023422 | 0.58 | HTT (0.44) | HTT | |
| SCHEMBL17875694 | 0.58 | CSNK2A1 (0.46) | HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-A2 | BROMODOMAIN INHIBITOR | Celgene Quanticel Research, Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168682-A2 | BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2016-10-20 | — | — | WO | disclosed |