Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | DHODH | Q02127 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18152624 | 0.81 | HTT (0.33) | ADRB2HTT | |
| SCHEMBL18152712 | 0.78 | GRIN2D (0.38) | HTT | |
| SCHEMBL18152662 | 0.70 | SCN9A (0.33) | — | |
| SCHEMBL18152677 | 0.69 | CCNB2 (0.32) | — | |
| SCHEMBL18152633 | 0.68 | USP30 (0.34) | — | |
| SCHEMBL18152783 | 0.65 | RIPK1 (0.33) | HTT | |
| SCHEMBL4381077 | 0.62 | HTT (0.47) | HTTDHODH | |
| SCHEMBL24589284 | 0.61 | ALDH1A1 (0.50) | — | |
| SCHEMBL15023422 | 0.60 | HTT (0.44) | HTTDHODH | |
| SCHEMBL21905305 | 0.59 | DHODH (0.70) | DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283077-A2 | BROMODOMAIN INHIBITOR | Celgene Quanticel Research, Inc. (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168682-A2 | BROMODOMAIN INHIBITOR | CELGENE QUANTICEL RESEARCH, INC. (US) | 2016-10-20 | — | — | WO | disclosed |