Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 14/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2230167 | 0.77 | TDP1 (0.52) | ALDH1A1TDP1GPR35 | |
| SCHEMBL1812445 | 0.76 | TDP1 (0.44) | HSD11B1ALDH1A1TDP1 | |
| SCHEMBL12357800 | 0.75 | HSD11B1 (0.52) | HSD11B1 | |
| SCHEMBL1812296 | 0.73 | HSD11B1 (0.82) | HSD11B1ALDH1A1 | |
| SCHEMBL17286709 | 0.72 | ESR1 (0.45) | HSD11B1 | |
| SCHEMBL15957680 | 0.72 | HSD11B1 (0.40) | HSD11B1ALDH1A1TDP1GPR35 | |
| SCHEMBL28563246 | 0.71 | HSD11B1 (0.40) | HSD11B1ALDH1A1TDP1 | |
| SCHEMBL12170410 | 0.71 | PTPRC (0.61) | HSD11B1ALDH1A1TDP1 | |
| SCHEMBL14574215 | 0.71 | PTPRC (0.61) | HSD11B1ALDH1A1TDP1 | |
| SCHEMBL1816541 | 0.71 | POLB (0.52) | HSD11B1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102177135-A | Acylaminobenzamide derivatives | BAYER CROPSCIENCE AG | 2011-09-07 | — | — | CN | disclosed |
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | BAYER CROPSCIENCE AG (DE) | 2011-08-18 | — | — | US | disclosed |
| EP-2318358-A2 | ACYLAMINOBENZAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2011-05-11 | — | — | EP | disclosed |
| WO-2010015355-A2 | NOVEL ACYLAMINOBENZAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-02-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110201603-A1 | Novel Acylaminobenzamide Derivatives | KCNB1, KCNA5, KCNA7 | HSD11B1 2117/4885ALDH1A1 271/4885TDP1 3523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.