Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 6/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.32 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | GRB2 | P62993 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9638271 | 0.81 | DGAT1 (0.41) | DGAT1PDE10AADRA2AADRA2BADRA2C | |
| SCHEMBL22441640 | 0.76 | TNK2 (0.37) | DGAT1PDE10ANPC1 | |
| SCHEMBL1126106 | 0.75 | TLR8 (0.47) | DGAT1NPC1 | |
| SCHEMBL7843607 | 0.75 | ESR1 (0.47) | DGAT1 | |
| SCHEMBL18865495 | 0.74 | DGAT1 (0.39) | DGAT1 | |
| SCHEMBL30671753 | 0.74 | DGAT1 (0.35) | DGAT1ADRA2AADRA2BADRA2C | |
| SCHEMBL2153326 | 0.74 | DGAT1 (0.40) | DGAT1ADRA2AADRA2BADRA2C | |
| SCHEMBL1441203 | 0.74 | DGAT1 (0.46) | DGAT1NPC1 | |
| SCHEMBL7507611 | 0.73 | PDE10A (0.45) | DGAT1PDE10ANPC1 | |
| SCHEMBL1488779 | 0.73 | KMT2A (0.43) | DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |