Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | CCNE1 | P24864 | 7/20 | 0.43 |
| ▸ | CDK2 | P24941 | 7/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | BCR | P11274 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | GALR2 | O43603 | 1/20 | 0.38 |
| ▸ | GALR1 | P47211 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153413 | 0.94 | PKM (0.50) | PKMCCNE1CDK2HSD17B10MAPK1 | |
| SCHEMBL18162450 | 0.86 | GALR2 (0.44) | PKMCCNE1CDK2HSD17B10ALDH1A1 | |
| SCHEMBL18162451 | 0.82 | HSD17B10 (0.44) | PKMCCNE1CDK2HSD17B10MAPK1 | |
| SCHEMBL18162560 | 0.82 | MAPT (0.49) | PKMCCNE1CDK2HSD17B10ALDH1A1 | |
| SCHEMBL18162508 | 0.79 | GALR2 (0.53) | PKMCCNE1CDK2HSD17B10MAPK1 | |
| SCHEMBL18153346 | 0.78 | CCNE1 (0.48) | CCNE1CDK2KMT2AMAPTMEN1 | |
| SCHEMBL18153299 | 0.78 | CCNE1 (0.48) | CCNE1CDK2KMT2AMAPTMEN1 | |
| SCHEMBL18153408 | 0.78 | BPTF (0.52) | CCNE1CDK2HSD17B10MAPK1ALDH1A1 | |
| SCHEMBL18162545 | 0.77 | KMT2A (0.58) | PKMHSD17B10MAPK1ALDH1A1TP53 | |
| SCHEMBL18153337 | 0.77 | KMT2A (0.51) | PKMCCNE1CDK2HSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |
| US-9085587-B2 | Inhibitors of hepatitis C virus | PRESIDIO PHARMACEUTICALS, INC. (US) | 2015-07-21 | — | — | US | disclosed |