Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 9/20 | 0.48 |
| ▸ | CDK2 | P24941 | 9/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | GALR2 | O43603 | 2/20 | 0.40 |
| ▸ | GALR1 | P47211 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18153366 | 0.88 | MAPT (0.51) | CCNE1CDK2MAPTGALR2GALR1 | |
| SCHEMBL18153346 | 0.86 | CCNE1 (0.48) | CCNE1CDK2MEN1BLMKMT2A | |
| SCHEMBL18153413 | 0.84 | PKM (0.50) | CCNE1CDK2MEN1BLMKMT2A | |
| SCHEMBL18153275 | 0.84 | GALR2 (0.48) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL18153404 | 0.78 | CCNE1 (0.42) | CCNE1CDK2MEN1BLMKMT2A | |
| SCHEMBL18153386 | 0.78 | PKM (0.46) | CCNE1CDK2MEN1BLMKMT2A | |
| SCHEMBL18153255 | 0.78 | SCN9A (0.44) | — | |
| SCHEMBL18153314 | 0.76 | LMNA (0.66) | CCNE1CDK2MEN1KMT2AMAPT | |
| SCHEMBL4730609 | 0.76 | ACHE (0.37) | KMT2APPARGTRPV1MAPTGALR2 | |
| SCHEMBL18162439 | 0.74 | ACHE (0.47) | CCNE1CDK2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3283472-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | Indiana University Research&Technology Corporation (US) | 2018-02-21 | — | — | EP | disclosed |
| WO-2016168619-A1 | HEPATITIS B VIRAL ASSEMBLY EFFECTORS | INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) | 2016-10-20 | — | — | WO | disclosed |