SCHEMBL18153858

SCHEMBL18153858

OC/C=C/C(O)C(O)CO

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
TDP1 Q9NUW8 1/20 0.43
KDM4E B2RXH2 2/20 0.32
PDE4A P27815 1/20 0.32
MEN1 O00255 3/20 0.31
MAPT P10636 3/20 0.31
KMT2A Q03164 3/20 0.31
GMNN O75496 2/20 0.31
GLA P06280 2/20 0.31
POLB P06746 2/20 0.31
THRB P10828 2/20 0.31
CETP P11597 2/20 0.31
MAPK1 P28482 2/20 0.31
CXCR5 P32302 2/20 0.31
CCR6 P51684 2/20 0.31
BLM P54132 2/20 0.31
UBE2N P61088 2/20 0.31
SPHK2 Q9NRA0 2/20 0.31
SPHK1 Q9NYA1 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18153861 1.00 LMNA (0.45) LMNAL3MBTL1TDP1KDM4EPDE4A
SCHEMBL11567483 0.82 MEN1 (0.31) LMNAMEN1MAPTKMT2AGMNN
SCHEMBL15536502 0.79 LMNA (0.41) LMNAL3MBTL1TDP1KDM4EMEN1
SCHEMBL15536501 0.79 LMNA (0.41) LMNAL3MBTL1TDP1KDM4EMEN1
SCHEMBL3689402 0.75 FPR2 (0.30)
SCHEMBL13813598 0.74
SCHEMBL7533938 0.74 FPR2 (0.33)
SCHEMBL8014415 0.72
SCHEMBL15010789 0.72
SCHEMBL11220283 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3227258-A1 A METHOD FOR SYNTHESIZING AN ALKENOIC ACID Agency For Science, Technology And Research (SG) 2017-10-11 EP claimed
WO-2016167726-A1 A METHOD FOR SYNTHESIZING AN ALKENOIC ACID AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2016-10-20 WO claimed
EP-3227258-A1 A METHOD FOR SYNTHESIZING AN ALKENOIC ACID Agency For Science, Technology And Research (SG) 2017-10-11 EP disclosed
WO-2016167726-A1 A METHOD FOR SYNTHESIZING AN ALKENOIC ACID AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2016-10-20 WO disclosed