SCHEMBL18153995

SCHEMBL18153995

Clc1cc(Cl)cc(C2CC2(Br)Br)c1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
KDM1A O60341 1/20 0.33
RCOR1 Q9UKL0 1/20 0.33
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18154022 0.84 TSHR (0.36) TSHRKDM1ARCOR1
SCHEMBL9839154 0.71 SLC6A2 (0.45)
SCHEMBL21078986 0.66 KDM1A (0.30) KDM1A
SCHEMBL21021685 0.66 MGLL (0.33) KDM1ARCOR1
SCHEMBL28853952 0.65 TSHR (0.42) TSHRKDM1ATP53CYP3A4
SCHEMBL1854233 0.65 KDM1A (0.54) KDM1A
SCHEMBL21418970 0.65 SLC6A2 (0.38)
SCHEMBL17713123 0.65 SLC6A2 (0.38)
SCHEMBL19626358 0.65 SLC6A2 (0.38)
SCHEMBL21418962 0.65 SLC6A2 (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow Agrosciences LLC (US) 2018-02-21 EP disclosed
WO-2016168059-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-10-20 WO disclosed