SCHEMBL18154022

SCHEMBL18154022

Clc1cc(Cl)cc([C@H]2C[C@@]2(Cl)Br)c1

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
KDM1A O60341 1/20 0.32
RCOR1 Q9UKL0 1/20 0.32
SLC9A1 P19634 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21078986 0.65 KDM1A (0.30) KDM1A
SCHEMBL21021685 0.64 MGLL (0.33) KDM1ARCOR1SLC9A1
SCHEMBL28853952 0.64 TSHR (0.42) TSHRKDM1A
SCHEMBL17725407 0.63 SLC6A2 (0.38)
SCHEMBL19626358 0.63 SLC6A2 (0.38)
SCHEMBL21418962 0.63 SLC6A2 (0.38)
SCHEMBL21418970 0.63 SLC6A2 (0.38)
SCHEMBL17713123 0.63 SLC6A2 (0.38)
SCHEMBL17724996 0.63 SLC6A2 (0.38)
SCHEMBL18146484 0.63 SLC9A1 (0.37) TSHRSLC9A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3283459-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO Dow Agrosciences LLC (US) 2018-02-21 EP disclosed
WO-2016168059-A1 MOLECULES HAVING PESTICIDAL UTILITY, AND INTERMEDIATES, COMPOSITIONS, AND PROCESSES, RELATED THERETO DOW AGROSCIENCES LLC (US) 2016-10-20 WO disclosed